GENERAL CLINICAL RESEARCH CENTER

全科临床研究中心

• 批准号: 3090037
• 负责人: DONALD F TAPLEY
• 金额: $ 166.63万
• 依托单位: COLUMBIA UNIV NEW YORK MORNINGSIDE
• 依托单位国家: 美国
• 财政年份: 1977
• 资助国家: 美国
• 起止时间: 1977-12-01 至 1995-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3090037
• 关键词: clinical trials; human subject

Continuation of the General Clinical Research Center for adult and pediatric patients at the Columbia-Presbyterian Medical Center in New York City is proposed for the purpose of providing a facility for multidisciplinary, intensive bedside clinical investigation of human disease. Support is requested for 1168 A days in the Adult Unit initially and 200 A days in the Pediatric Unit; a metabolic diet kitchen; a discrete Outpatient Unit with 3750 annual visits initially; a Core Laboratory, and a computer-based data management and analysis resource. The Center is designed so that acutely ill, as well as ambulatory patients can be studied. The Center provides for hospitalization of patients in a setting in which careful dietary control, skillful intensive nursing care, and precise collection of urine, stool, and blood specimens, as well as other special procedures, can be carried out. Qualified faculty members of the clinical and basic science departments of the College of Physicians and Surgeons, Columbia University will study clinical problems which embrace most of the major fields of clinical investigation. Although the primary purpose of the facility is concerned with human research, it also provides unusual opportunities for undergraduate and postgraduate training in clinical investigation. Major research activities include: Lipid and Lipoprotein metabolism; Dementias, especially Alzheimer's disease; Parkinson's Disease; Reproductive Biology; AIDS; Lead Intoxication; Infant Nutrition and Energy Expenditure; Cardiac Arrhythmias; Cardiac Transplantation; Obesity; Osteoporosis; Hyperparathyroidism; Hemolytic Anemias; Myocardial Ischemia; Psoriasis; Paget's Disease of Bone; Anorexia Nervosa; Preeclampsia; and Neuromuscular Disease.

成人和普通临床研究中心的延续 纽约哥伦比亚长老会医疗中心的儿科患者 提议城市的目的是为 人类的多学科、密集的床边临床研究 疾病。 最初在成人科需要 1168 A 天的支持 在儿科病房工作 200 天；代谢饮食厨房；离散的 初期年门诊量3750人次；一个核心实验室，以及 基于计算机的数据管理和分析资源。 该中心是 旨在使重症患者以及卧床患者能够 研究过。 该中心为患者提供住院治疗 其中，严格的饮食控制、熟练的重症护理以及 精确采集尿液、粪便和血液样本以及其他样本 特殊程序，可以进行。 合格的教职人员 医师学院的临床和基础科学系 哥伦比亚大学的外科医生将研究临床问题，其中包括 临床研究的大多数主要领域。 虽然初级 该设施的目的与人类研究有关，它还提供 本科生和研究生培训的难得机会 临床调查。 主要研究活动包括：脂质和脂蛋白代谢； 痴呆症，尤其是阿尔茨海默病；帕金森病； 生殖生物学；艾滋病;铅中毒；婴儿营养和能量 支出;心律失常；心脏移植；肥胖; 骨质疏松症；甲状旁腺功能亢进;溶血性贫血；心肌缺血； 银屑病;佩吉特骨病；神经性厌食症；先兆子痫；和 神经肌肉疾病。