ADOPTIVE IMMUNTHERAPY FOR RELAPSED CHRONIC MYELOGENOUS LEUKEMIA

复发性慢性粒细胞白血病的过继免疫治疗

• 批准号: 3788818
• 负责人: JOSEPH ANTIN
• 金额: --
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3788818
• 关键词: bone marrow transplantation; chronic myelogenous leukemia; clinical trials; disease /disorder proneness /risk; graft versus host disease; human subject; human therapy evaluation; neoplasm /cancer chemotherapy; neoplasm /cancer immunotherapy; neoplasm /cancer relapse /recurrence; neoplasm /cancer remission /regression; passive immunization

The goals of this study are 1) to determine the risk of graft vs. host disease, 2) to determine the ability of this therapy to result in long term hematologic and cytogenetic remissions, 3) to compare the results of this treatment to historical controls treated with second bone marrow transplantation or conventional chemotherapy and/or immunotherapy.

本研究的目的是1）确定移植物抗宿主的风险 疾病，2）以确定这种疗法的能力，以导致长期 长期血液学和细胞遗传学缓解，3）比较结果 与使用第二骨髓处理的历史对照相比， 移植或常规化疗和/或免疫治疗。