ALLOGENEIC BMT FOR HODGKIN'S DISEASE AND NONHODGKIN'S LYMPHOMA

霍奇金病和非霍奇金淋巴瘤的同种异体骨髓移植

• 批准号: 3766609
• 负责人: JOSEPH ANTIN
• 金额: --
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3766609
• 关键词: Hodgkin's disease; antineoplastics; bone marrow transplantation; carmustine; clinical trials; combination cancer therapy; cyclophosphamide; dosage; etoposide; homologous transplantation; human subject; human therapy evaluation; neoplasm /cancer chemotherapy; neoplasm /cancer radiation therapy; nonHodgkin's lymphoma

This is a Phase II trial of high dose chemotherapy and allogeneic BMT for patients with Hodgkin's or non-Hodgkin's Lymphoma who have had pelvic irradiation or marrow involvement and who cannot receive autologous transplants. The conditioning regimen uses cyclophosphamide, BCNU, and etoposide in high doses, since most eligible patients have had thoracic radiation therapy.

这是一项高剂量化疗和同种异体骨髓移植用于 患有霍奇金或非霍奇金淋巴瘤的患者， 放射或骨髓受累，不能接受自体移植的患者 移植预处理方案使用环磷酰胺，BCNU， 高剂量的依托泊苷，因为大多数符合条件的患者有胸 放射治疗