CONTINUOUS INFUSION CYCLOSPORINE IN MARROW TRANSPLANTATION FOR MYELODYSPLASIA

连续输注环孢素在骨髓增生异常骨髓移植中的应用

• 批准号: 3766675
• 负责人: JOSEPH ANTIN
• 金额: --
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3766675
• 关键词: bone marrow transplantation; chemoprevention; cyclosporines; drug administration rate /duration; drug screening /evaluation; dyserythropoietic anemia; graft versus host disease; human subject; human therapy evaluation; immunosuppressive; injection /infusion; methotrexate

The purpose of this study is to evaluate the safety and efficacy of continuous infusion cyclosporine (CSA) and 5 doses of weekly methotrexate in the prophylaxis of acute Graft-versus-Host Disease (GvHD) in patients with myelodysplasia syndromes (MDS).

这项研究的目的是评估 连续输注环孢菌素（CSA）和5剂每周甲氨蝶呤 在患者的急性移植抗宿主病（GVHD）的预防中 伴有骨髓增生综合征（MDS）。