BMY-27857 (2'3'-DIDEHYDRO-3'-DEOXYTHYMIDINE, D4T) ADMINISTERED TO HIV+ PATIENTS

BMY-27857（23-二氢-3-脱氧胸苷，D4T）用于 HIV 患者

• 批准号: 3849039
• 负责人: HENRY S SACKS
• 金额: --
• 依托单位: MOUNT SINAI SCHOOL OF MEDICINE OF CUNY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3849039
• 关键词: 2'3' dideoxynucleoside; AIDS; AIDS therapy; HIV infections; antiAIDS agent; drug administration rate /duration; drug screening /evaluation; human subject; human therapy evaluation; immunopathology chemotherapy; oral administration; pharmacokinetics

Study objectives are to determine the safety of oral doses of BMY-27857 (D4T) administered three times a day to patients with symptomatic HIV infection, to establish pharmacokinetic parameters for D4T.

研究目标是确定口服剂量的BMY-27857的安全性 (D4T)对有症状的HIV患者每天三次 感染，建立d4T的药代动力学参数。