Defining the contribution of A-to-I RNA editing by ADAR’s in physiology and disease
Defining the contribution of A-to-I RNA editing by ADAR’s in physiology and disease
批准号:
nhmrc : 1144049
负责人:
A/Pr Carl Walkley
金额:
$49.23万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2020-12-31
中文摘要
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英文摘要
We are working on understanding how a family of proteins called ADARs work. ADAR proteins can change the sequence of the cells RNA. When they are mutated or more than normal amounts are expressed in a cell it appears they can cause a range of diseases in humans. We are trying to determine how changes in the level or activity of ADAR proteins may contribute to disease.
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Defining the contribution of A-to-I RNA editing by ADAR’s in physiology and disease
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批准号:nhmrc : GNT1144049
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项目类别:Project Grants
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资助金额:$72.82万
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财政年份:2018
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负责人:A/Pr Carl Walkley
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依托单位:
Understanding the function of Recql4 in DNA replication and genome maintenance
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批准号:nhmrc : GNT1126004
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项目类别:Project Grants
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资助金额:$69.84万
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财政年份:2017
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负责人:A/Pr Carl Walkley
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依托单位:
Microenvironmental regulation of blood cells by retinoic acid receptor gamma.
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批准号:nhmrc : 1127551
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项目类别:Project Grants
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资助金额:$65.45万
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财政年份:2017
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负责人:A/Pr Carl Walkley
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依托单位:
Microenvironmental regulation of blood cells by retinoic acid receptor gamma.
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批准号:nhmrc : GNT1127551
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项目类别:Project Grants
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资助金额:$95.84万
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财政年份:2017
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负责人:A/Pr Carl Walkley
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依托单位:
Understanding the function of Recql4 in DNA replication and genome maintenance
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批准号:nhmrc : 1126004
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项目类别:Project Grants
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资助金额:$47.66万
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财政年份:2017
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负责人:A/Pr Carl Walkley
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依托单位:
Why does endogenous RNA need A-to-I editing?
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批准号:nhmrc : 1102006
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项目类别:Project Grants
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资助金额:$54.43万
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财政年份:2016
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负责人:A/Pr Carl Walkley
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依托单位:
Why does endogenous RNA need A-to-I editing?
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批准号:nhmrc : GNT1102006
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项目类别:Project Grants
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资助金额:$79.43万
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财政年份:2016
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负责人:A/Pr Carl Walkley
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依托单位:
Targeting the PTHrP?PTHR1?CREB axis as a therapeutic approach in osteosarcoma
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批准号:nhmrc : 1084230
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项目类别:Project Grants
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资助金额:$44.6万
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财政年份:2015
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负责人:A/Pr Carl Walkley
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依托单位:
Role of a DNA helicase, Recql4, in haematopoiesis, skeletal biology and malignancy
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批准号:nhmrc : 1065002
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项目类别:Project Grants
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资助金额:$50.06万
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财政年份:2014
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负责人:A/Pr Carl Walkley
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依托单位:
Myelodysplastic syndrome and the bone marrow microenvironment
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批准号:nhmrc : 1031481
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项目类别:Project Grants
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资助金额:$37.52万
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财政年份:2012
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负责人:A/Pr Carl Walkley
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依托单位:
Defining the role of RNA editing in erythropoiesis
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批准号:nhmrc : 1021216
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项目类别:Project Grants
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资助金额:$41.94万
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财政年份:2012
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负责人:A/Pr Carl Walkley
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依托单位:
Effects of Ephrin-Eph and PTHrP signalling on osteosarcoma.
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批准号:nhmrc : 620203
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项目类别:NHMRC Project Grants
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资助金额:$43.11万
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财政年份:2010
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负责人:A/Pr Carl Walkley
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依托单位:
The Role of Cell Cycle Control in Haemopoietic Stem Cell Fate Decisions.
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批准号:nhmrc : 559016
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项目类别:Career Development Fellowships
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资助金额:$26.07万
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财政年份:2009
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负责人:A/Pr Carl Walkley
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依托单位:
Cell Cycle Regulation, Haemopoietic Stem Cells and Myeloproliferation.
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批准号:nhmrc : 559018
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项目类别:NHMRC Project Grants
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资助金额:$38.62万
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财政年份:2009
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负责人:A/Pr Carl Walkley
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依托单位:
Characterisation of a new model of Osteosarcoma
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批准号:nhmrc : 559019
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项目类别:NHMRC Project Grants
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资助金额:$37.21万
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财政年份:2009
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负责人:A/Pr Carl Walkley
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依托单位:
海外基金