FLUORIDE MOUTHRINSING AND FLUORIDE TABLETS USED SEPARATELY AND IN COMBINATION

氟化物漱口剂和氟化物片剂单独和组合使用

• 批准号: 3854189
• 负责人: W S DRISCOLL
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3854189
• 关键词: child (0-11); dental caries inhibitor; dosage forms; elementary school; human subject; human therapy evaluation; ingested fluoride therapy; longitudinal human study; mouthwash; preventive dentistry; self medication; topical fluoride therapy

In September 1981, a study designed to compare the caries-preventive effects of a combined regimen of weekly fluoride rinsing and daily fluoride tablets with those of each procedure used alone was begun in Springfield, Ohio, a fluoride-deficient community. The approximately 1700 children attending 20 public and non-public elementary schools were randomly assigned to one of three treatment groups. The children in Group I dissolved and ingested daily a 1 mg F tablet; the children in Group III rinsed weekly with a 0.2% NaF solution; and Group II carried out both procedures. The assigned treatments were self-administered under the supervision of classroom teachers who received in-service training. Before the procedures were started, baseline DMFS examinations were conducted. First and second follow-up examinations were conducted in October 1983 and November 1986 respectively. Final DMFS examinations were conducted in May 1989. Data from this exam have been analyzed and a report has been submitted to a scientific dental journal for publication.

1981年9月，一项旨在比较预防龋齿的研究