FLUORIDE MOUTHRINSE AND FLUORIDE TABLETS USED SEPARATE AND COMBINED

氟化物漱口水和氟化物片剂单独和组合使用

• 批准号: 3839189
• 负责人: W S DRISCOLL
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3839189
• 关键词: child (0-11); dental caries; dental caries inhibitor; elementary school; fluorosis; human subject; ingested fluoride therapy; longitudinal human study; mouthwash; preventive dentistry

In September 1981, a study designed to compare the caries-preventive effects of a combined regimen of weekly fluoride rinsing and daily fluoride tablets with those of each procedures used alone was begun in Springfield, Ohio, a fluoride-deficient community. The approximately 1700 children attending 20 public and non-public elementary schools were randomly assigned to one of three treatment groups. The children in Group I dissolved and ingested daily a 1 mg F tablet; the children in Group III rinsed weekly with a 0.2% NaF solution; and Group II carried out both procedures. The assigned treatments were self-administered under the supervision of classroom teachers who received in-service training. Before the procedures were started, baseline DMFS examinations were conducted. First and second follow-up examinations were conducted in October 1983 and November 1986 respectively. Final DMFS examinations were conducted in May 1989. Data from this exam have been analyzed and a report has been published. Follow-up examinations for dental fluorosis were conducted in February 1992. Following completion of data analysis, a final report will be prepared.

1981年9月，一项旨在比较预防龋齿的 每周氟冲洗和每日氟冲洗联合方案的效果 氟片剂与每一个程序单独使用的开始， 俄亥俄州的斯普林菲尔德，一个缺氟社区。 的大约 在20所公立和非公立小学就读的1700名儿童， 随机分配到三个治疗组之一。 的孩子 组I溶解并每日摄入1 mg F片剂; 组III每周用0.2%NaF溶液冲洗;组II携带 这两个程序。 分配的治疗为自我给药 在在职教师的监督下， 训练 在手术开始前， 进行。 第一次和第二次随访检查在 1983年10月和1986年11月。 DMFS期末考试 于1989年5月进行。 对本次考试的数据进行了分析， 已经发表了一份报告。 牙科随访检查 1992年2月进行了氟中毒研究。 数据完成后 分析后，将编写一份最终报告。