FLUORIDE MOUTHRINSING AND FLUORIDE TABLETS USED SEPARATELY AND IN COMBINATION

氟化物漱口剂和氟化物片剂单独和组合使用

• 批准号: 3917108
• 负责人: W S DRISCOLL
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3917108
• 关键词: dental caries inhibitor; dosage forms; human subject; human therapy evaluation; ingested fluoride therapy; mouthwash; preschool child (1-5); preventive dentistry; topical fluoride therapy

In September 1981, a self-administered dental program was begun in Springfield, Ohio, a fluoride-deficient community. The approximately 1700 children attending 20 public and non-public elementary schools were randomly assigned to one of three treatment groups. The children in Group I dissolve and ingest daily a 1 mg F tablet; the children in Group III rinse weekly with a 0.2% NaF solution; and Group II carries out both procedures. The assigned treatments are self-administered under the supervision of the teacher. Before the procedures were started, baseline examinations were conducted. First and second follow-up dental examinations were conducted in October 1983 and November 1986 respectively. The procedures will be continued through 1989 and followed by a clinical examination. Three to four years following the cessation of treatment, a post-treatment examination will be conducted in high school to determine the extent of continued protection. Supplies have been ordered, schedules arranged and local personnel identified for the start of the eighth school year of treatment in October 1988. Clinical examinations will be conducted in May 1989.

在1981年9月，一个自我管理的牙科计划开始， 俄亥俄州的斯普林菲尔德，一个缺氟社区。 的 约1 700名儿童参加20个公立和非公立学校 小学被随机分配到三个治疗之一， 组 第一组的儿童每天溶解并摄入1毫克 第三组儿童每周用0.2%NaF漱口 解决方案;和第二组进行两个程序。 所分配的 治疗是自我管理的监督下， 老师 在手术开始前， 进行。 第一次和第二次随访牙科检查是 分别于1983年10月和1986年11月进行。 的 程序将持续到1989年，然后是一个 临床检查 停止后三至四年 治疗结束后，将进行治疗后检查， 高中确定继续保护的程度。 已经订购了用品，安排了时间表， 第八学年开始时确定的 一九八八年十月。 临床检查将于1989年5月进行。