EFFICACY OF DDI FOR AIDS OR ARC PATIENTS INTOLERANT TO ZDV

DDI 对不耐受 ZDV 的艾滋病或 ARC 患者的疗效

• 批准号: 3863989
• 负责人: Fred T Valentine
• 金额: --
• 依托单位: NEW YORK UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3863989
• 关键词: 2'3' dideoxynucleoside; AIDS; AIDS therapy; clinical trials; dosage; drug adverse effect; drug tolerance; human immunodeficiency virus; human subject; human therapy evaluation; zidovudine

This study will evaluate the efficacy and toxicity of three doses of orally administered ddI in the treatment of patients with AIDS and advanced ARC who have demonstrated hematological intolerance to zidovudine. It will also determine if the efficacy of ddI increases with increasing dose.

本研究将评估三种剂量的口服 给予ddI治疗艾滋病和晚期ARC患者 对齐多夫定有血液学不耐受它还将 确定ddI的疗效是否随剂量增加而增加。