Center for AIDS Research

描述（由申请人提供）：纽约大学医学中心艾滋病研究中心由70名临床和基础科学研究人员组成，他们在曼哈顿下城的三个连续机构和河对岸的纽瓦克的一个机构进行研究。这些科学家隶属于纽约大学医学院，尽管他们的实验室和研究诊所位于曼哈顿VA医院、贝尔维尤医院、纽约公共卫生研究所以及医学院大楼，包括Tisch医院和Skirball研究所。自从1980年纽约大学的研究人员发现了他们的第一个病人以来，他们对我们对这种疾病的病毒学、免疫学、流行病学、感染和肿瘤并发症的理解做出了许多重要的贡献。纽约大学的临床医生正在治疗4000多名艾滋病毒感染者，我们的临床研究工作从整个大都会地区数千名艾滋病毒阳性受试者中吸引了更多的患者。这项研究目前得到了2500多万美元艾滋病相关基金的支持，其中包括每年来自美国国立卫生研究院的1500多万美元资金。CFAR支持这一富有成效的研究项目，并通过四个共享的核心设施和发展基金来提高其效率，以支持年轻的研究人员和新的研究机会。CFAR还将具有相似兴趣的研究人员聚集到几个研究项目中，以促进创新和合作。

DESCRIPTION (provided by applicant): The Center for AIDS Research at NYU Medical Center comprises seventy clinical and basic science investigators performing research in three contiguous institutions in lower Manhattan and one across the river in Newark. These scientists are affiliated with the NYU School of medicine, although their laboratories and research clinics are located at the Manhattan VA Hospital, Bellevue Hospital, the New York Public Health Research Institute, as well as the School of Medicine buildings, including Tisch Hospital and Skirball Institute. Many important contributions to our understanding of the virology, immunology, epidemiology, and the infections and neoplastic complications of this disease have been made by NYU investigators since they identified their first patient in 1980. NYU clinicians are caring for over 4,000 HIV-infected individuals, and our clinical research efforts attract additional patients from the several thousands of HIV + subjects throughout the metropolitan region. This research is currently supported by over $25 M in AIDS-related funding, which includes over $15 M in yearly funding from the NIH. The CFAR supports this productive program of research and increases its efficiency by four shared core facilities, and developmental funds to support young investigators and new research opportunities. The CFAR also brings together investigators with similar interests into several research programs to facilitate innovation and collaboration. CORE A: Administrative Core (Valentine, F) DESCRIPTION (provided by applicant): The Administration Unit (Core) provides overall leadership and administrative management to the CFAR. The Administration is directed by Fred Valentine, M.D., with the support of two Associate Directors, Dan Littman, M.D., Ph.D. for Basic Science and William Borkowsky, M.D., for Clinical Research. The responsibilities of the Administration fall into two categories: 1) Providing proactive leadership in expanding HIV-related collaborative and translational research, 2) Ensuring that the multiple elements of the Center function together as a Center, that the whole is in fact greater than the sum of its parts. The senior leadership establishes the goals of the Center and, through the Center's programmatic and core structure, creates the optimal environment for interaction, growth and support of HIV research. The Director also works with the Administrators, Ms. Andrea Barrett and Irini Albanti, to ensure the smooth operation of the Center's chief administrative functions. These include: policies to guide the CFAR operations; budgetary stewardship; internal and external communication systems; planning and evaluation of CFAR activities, helping investigators and working with the development office on fund raising for CFAR. The Administrative Core functions primarily to provide the administrative support systems and management tools needed to maintain the CFAR's activities. This Core is responsible for fostering and tracking the scientific productivity and progress of its members. The Core also organizes and expands our outreach and international scientific and educational activities.