THRESHOLD TO CEILING EFFECTS OF CHOLESTEROL ON LIPOPROTEIN AND LDL TURNOVER

胆固醇对脂蛋白和低密度脂蛋白周转率影响的上限阈值

• 批准号: 3864927
• 负责人: WILLIAM E. CONNOR
• 金额: --
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3864927
• 关键词: apolipoproteins; blood lipoprotein metabolism; cholesterol; dietary control; dietary lipid; human subject; lipid metabolism; low density lipoprotein; nutrient requirement; nutrition related tag

It is important to identify and quantitate the threshold and ceiling levels of dietary cholesterol to enable sound dietary recommendations. There will be three dietary periods: a nearly cholesterol-free baseline period, a high cholesterol diet period and an intermediate level of dietary cholesterol. We hypothesize that the "ceiling" concept will explain the many conflicting results reported in the literature on cholesterol feedings and detailed in the section to follow.

重要的是确定和量化阈值和上限水平