HIGH RESOLUTION IMAGE DIGITIZATION AND ANALYSIS SYSTEM

这是一个申请购买高分辨率图像的资金 数字化和分析系统将用于至关重要的实验 这项研究是在爱荷华大学进行的。这些设备 所需设备包括一台数码相机、一个成像工作站、一张磁盘 服务器和多个输出设备。拟议的文书将是 位于爱荷华大学图像分析设施中，这是一个 大学核心设施向所有教职员工提供并运营 由一位科学可视化专家。 一百多个不同的研究小组参与了广泛的 研究项目利用图像处理和图形建模 安装在图像分析设施中的系统。其中，有七大 用户参与了总共11个不同的小灵通资助的项目， 在分辨率和敏感度方面受到严重限制 由过时的设备进行的实验图像测量 目前正在使用。所要求的成像和图形系统已经 精心挑选以补充现有能力并 满足这组研究人员和其他人的需求 计划扩展到这项技术。 将立即受益于该计划的项目说明 提供了所需的设备。塔尔曼正在量化和可视化 注射药物向大鼠迷走神经背侧复合体的扩散。 Andreasen正在绘制多巴胺能和血清胺能受体系统图 死后精神分裂症，脑叶切除，正常人脑。华纳 正在可视化和测量不同麻醉剂对 中风患者的血液流动。库尔塔斯-伊林斯基正在对GABA进行量化 结合到神经结构上。托德正在测量麻醉的效果 关于血液流动的。弗朗茨正在监测伤口愈合实验。贾妮是 成像近距离放射治疗植入物的等剂量场。支持 购买拟议的仪器将允许进行分析 目前在爱荷华大学是可能的。

This is an application for funds to purchase a high resolution image digitizing and analysis system to be used in experiments vital to research being performed at the University of Iowa. The equipment requested includes a digital camera, one imaging workstation, a disk server and several output devices. The proposed instrument will be housed in the University of Iowa Image Analysis Facility, which is a university core facility available to all faculty and staff and operated by a scientific visualization specialist. Over one hundred different research groups involved in a wide range of research projects utilize the image processing and graphics modelling systems housed in the Image Analysis Facility. Of these, seven major users are involved in a total of 11 different PHS funded projects which are severely restricted in the resolution and sensitivity of their experimental image measurements by the outdated equipment they are currently using. The requested imaging and graphics system has been carefully selected to complement the existing capabilities and to fulfill the needs of this group of researchers, and others who are planning to expand into this technology. The descriptions of projects which would benefit immediately from the equipment requested is provided. Talman is quantizing and visualizing diffusion of injected agents into the dorsal vagal complex of rats. Andreasen is mapping dopaminergic and sertoninergic receptor systems in post mortem schizophrenic, lobotomized, and normal human brains. Warner is visualizing and measuring the effects of different anesthetics on blood flow in stroke victims. Kultas-Ilinsky is quantifying GABA binding to neurostructures. Todd is measuring the effects of anesthesia on blood flow. Frantz is monitoring wound healing experiments. Jani is imaging the isodose fields of brachytherapy implants. Support for the purchase of the proposed instrument would allow for analysis not currently possible at the University of Iowa.