INTRAVENOUS GAMMAGLOBULIN THERAPY IN TREATMENT OF HIV-INFECTED CHILDRENN

静脉注射丙种球蛋白疗法治疗艾滋病毒感染儿童

• 批准号: 3884858
• 负责人: KEITH KRASINSKI
• 金额: --
• 依托单位: NEW YORK UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3884858
• 关键词: HIV infections; antiAIDS agent; antibiotics; bacterial disease; child (0-11); clinical trials; drug administration routes; gamma globulin; human subject; human therapy evaluation; immunotherapy; injection /infusion; opportunistic infections; virus diseases

This study will determine if a monthly intravenous immunoglobulin administration, compared to intravenous placebo, will significantly reduce the rate of serious, life-threatening bacterial infections in HIV-infected children, if it will reduce the rate of viral, opportunistic and minor infections, days of hospitalization, days of antibiotic use and progression of HIV disease.

这项研究将确定每月静脉注射免疫球蛋白 与静脉注射安慰剂相比，给药将显著减少 艾滋病毒感染者中严重的、危及生命的细菌感染率 儿童，如果这将降低病毒性、机会性和未成年人的发病率 感染、住院天数、抗生素使用天数和病情进展 感染艾滋病毒的人。