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PATHOPHYSIOLOGY OF DISTAL SENSORY PERIPHERAL NEUROPATHY (DSPN) OF AIDS

PATHOPHYSIOLOGY OF DISTAL SENSORY PERIPHERAL NEUROPATHY (DSPN) OF AIDS
艾滋病远端感觉周围神经病变（DSPN）的病理生理学
批准号：
3887350
负责人：
FREDERICK T KOSTER
金额：
$0.0万
依托单位：
UNIVERSITY OF NEW MEXICO
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3887350
关键词：
AIDS edema hereditary sensory neuropathy human subject magnetic resonance imaging medical complication nervous system disorder diagnosis neural transmission

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英文摘要
DSPN of AIDS appears to be a drying back neuropathy, similar to that of diabetes. Preliminary evidence indicates an increase in endoneurial water present in the early stages of disease, and we hypothesize that nerve edema contribute to the pathogenesis of nerve injury. We propose to quantitate nerve water by magnetic resonance spectroscopy, and compare these results with nerve conduction velocity and physical exam.
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