Defining the unifying mechanisms of oxidative damage to oligodendrocyte DNA in neurotrauma, neurodegenerative and demyelinating disease
Defining the unifying mechanisms of oxidative damage to oligodendrocyte DNA in neurotrauma, neurodegenerative and demyelinating disease
定义神经外伤、神经退行性和脱髓鞘疾病中少突胶质细胞 DNA 氧化损伤的统一机制
批准号：
nhmrc : GNT1160691
负责人：
金额：
$124.51万
依托单位：
依托单位国家：
澳大利亚
项目类别：
Project Grants
财政年份：
2019
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2019-01-01 至 --
中文摘要
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英文摘要
Damage following injury to the central nervous system, and in Alzheimer’s Disease and Multiple sclerosis is similar and may be triggered by loss of the insulation around nerve cells, called myelin. We aim to identify a common mechanism by which the myelinating cells die and function is lost in the three conditions, enabling us to design a treatment that may be effective across the spectrum of injury and disease in the central nervous system.
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