课题基金 / 基金详情

CIRCULAR DICHROISM SPECTROPOLARIMETER

CIRCULAR DICHROISM SPECTROPOLARIMETER
圆二色性分光偏振仪
批准号:
3520398
负责人:
EMIL REISLER
金额:
$13.0万
依托单位国家:
美国
项目类别:
财政年份:
1989
资助国家:
美国
项目状态:
已结题
起止时间:
1989-05-08 至 1990-05-07

项目摘要

项目成果

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相关文献

中文摘要
翻译
圆二色性(CD)测量是最有价值的测量方法之一
英文摘要
Circular dichroism (CD) measurements are one of the most valuable sources of structural and conformational information on solutions of chemical and biochemical compounds. Recent improvements in instrumentation have further enhanced the usefulness of this technique in chemical and biochemical research. This proposal is for the purchase of a modern CD spectropolarimeter to be used by a large number of researchers. Problems under investigation by the prime user group are 1) structures of myosin and actin and muscle contraction, 2) structural analysis of ubiquitin-protein conjugates, 3) complexes of drug molecules and carcinogens with double stranded DNA, 4) oligomerization of melittin and peptides from HIV gp41, 5) eye lens proteins and other proteins of the visual system, 6) electrostatic properties of the alpha-helix, 7) two dimensional structure of apolipoprotein B on the surgace of the low density lipoprotein, 8) molecular analysis, synthesis, and folding of defensins, and 9) synthesis of sequence specific nucleases. The proposed purchase of CD equipment will fulfill acute research needs for this type of insurumentation by NIH- supported investigators at UCLA.
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会议论文
Dynamic Events in Myosin and Actin and Their Function
PURCHASE OF MICROCALORIMETRY EQUIPMENT
DYNAMIC EVENTS IN MYOSIN DURING CONTRACTION OF MUSCLE
DYNAMIC EVENTS IN MYOSIN DURING CONTRACTION OF MUSCLE
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