Dendritic cells and CCAAT/enhancer binding protein-delta (CEBP?) in neuroinflammation and autoimmunity

树突状细胞和 CCAAT/增强子结合蛋白-δ (CEBP?) 在神经炎症和自身免疫中的作用

• 批准号: nhmrc : 1057912
• 负责人: Prof David Brown
• 金额: $ 38.44万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/dendritic-cells-ccaatenhancer-neuroinflammation-autoimmunity/454645
• 关键词: Dendritic; cells; CCAAT; enhancer; binding

This projects aims to develop new treatments by finding the cells and chemicals that naturally stop inflammation in the central nervous system in diseases like MS. It also aims to test new treatments by delivering them to where this inflammation takes place. This targeted delivery should mean fewer side effects because the rest of the body is not exposed to the treatment. Hopefully this will reduce the impact of these diseases on the community, and reduce side effects for the patient.

该项目旨在开发新的治疗方法，通过寻找能够自然阻止MS等疾病的中枢神经系统炎症的细胞和化学物质。它还旨在通过将它们输送到炎症发生的地方来测试新的治疗方法。这种定向给药应该意味着副作用更少，因为身体的其他部分不会暴露在治疗中。希望这将减少这些疾病对社区的影响，并减少对患者的副作用。