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KETONE FALSE-POSITIVES WITH THE DRUG MESNA AND OTHER FREE-SULFHYDRYL COMPOUNDS

KETONE FALSE-POSITIVES WITH THE DRUG MESNA AND OTHER FREE-SULFHYDRYL COMPOUNDS
酮与药物美司钠和其他游离巯基化合物的误报
批准号:
3916526
负责人:
G CSAKO
金额:
$0.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
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中文摘要
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英文摘要
The Legal test (acetoacetic acid and/or acetone and sodium nitroprusside in alkaline medium) was studied for interference with the uroprotective drug mesna and related compounds. All free- sulfhydryl compounds tested produced false-positive reactions in this test for ketones. The presence of acidic groups in the structure appeared to increase the nitroprusside reactivity of free sulfhydryl compounds, whereas the presence of an amino group appeared to decrease it. Procedures have been elaborated to recognize and rule out false-positive ketone reactions with these compounds in clinical specimens.
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  • 批准号:
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  • 项目类别:
  • 资助金额:
    $0.0万
  • 财政年份:
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  • 负责人:
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  • 项目类别:
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  • 财政年份:
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  • 财政年份:
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  • 负责人:
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  • 依托单位:
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