MEPERIDINE AND LOCAL ANESTHETICS IN BREAST MILK

母乳中的哌替啶和局部麻醉剂

• 批准号: 3926413
• 负责人: BETTY R. KUHNERT
• 金额: --
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3926413
• 关键词: blood chemistry; colostrums; drug adverse effect; drug metabolism; embryo /fetus drug adverse effect; embryo /fetus pharmacology; human fetus tissue; human milk; human subject; local anesthetics; meperidine; neurologic manifestations; newborn human (0-6 weeks); pharmacokinetics; urinalysis

The purpose of this study is to quantitate the levels of meperidine and bupivacaine in colostrum and breast milk in neonatal plasma and urine and to determine their effects on neonatal behavior. The study includes fetal exposure to meperidine and bupivacaine intrapartum, and neonatal exposure to meperidine administered to the mother for post partum relief.

本研究的目的是定量哌替啶的水平