Multiple sclerosis and the HLA region. Functional genetics.

多发性硬化症和 HLA 区域。

• 批准号: G0800500/1
• 负责人: Lars Fugger
• 金额: $ 107.57万
• 依托单位: University of Oxford
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2010
• 资助国家: 英国
• 起止时间: 2010 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G0800500%2F1
• 关键词: Multiple; sclerosis; HLA; region.; Functional

Multiple sclerosis (MS) is a neurological disease, which often affects young women. There is no effective treatment for MS. To develop new drugs it is necessary to understand in detail what kind of disease MS is. It has been known for many year that there is a strong genetic component in MS, and there have been many attempts to identify the actual genes that predispose to the disease.We will study a number of genes that play roles in the immune-response to shed light on which part of the immunesystem that contribute to the development of MS.

多发性硬化症（MS）是一种神经系统疾病，通常影响年轻女性。MS没有有效的治疗方法，为了开发新药，有必要详细了解MS是什么样的疾病。多年来，人们已经知道MS中有很强的遗传成分，并且已经进行了许多尝试来确定易患该疾病的实际基因。我们将研究一些在免疫反应中发挥作用的基因，以阐明免疫系统的哪一部分有助于MS的发展。