DPFS Resource request (King s College London)

DPFS 资源请求（伦敦国王学院）

• 批准号: G0801674/1
• 负责人: Stuart Bevan
• 金额: $ 33.44万
• 依托单位: King's College London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2009
• 资助国家: 英国
• 起止时间: 2009 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G0801674%2F1
• 关键词: DPFS; Resource; request; King; College

The application of basic medical research results to improve the health of patients is a main goal of modern medical science. In order to do this, it is essential that we identify the best scientific ideas that can lead to the development of novel therapies and improved ways to diagnose diseases and predict the effectiveness of different treatments. The development or translation of these basic discoveries into applications (translational research) is the aim of the MRC?s Developmental Pathway Funding Scheme (DPFS). King?s College London is committed to translational research and has invested heavily in both staff and facilities to promote and support our activities in this area. Given the strong interest in translational research at King?s, we expect that our scientists will submit a large number of applications to the scheme and that we will have a significant number of funded projects running. The DPFS projects have in-built milestones, which can be used to measure progress of the research, and Go/No Go points where the project can be stopped if the expected progress is not achieved. Most academic scientists have limited experience in such translational, milestone based projects. We are requesting underpinning resources for devolved portfolio support to recruit a member of portfolio support staff to manage the King?s applications and funded projects. A member of portfolio support staff based at King?s will be able to interact with the scientists prior to applying for DPFS grants to ensure that proposals have a strong translational potential with realistic milestones and decisions points. Locally based staff will oversee the King?s projects and assist the scientists with project management. This oversight will allow the progress of each project to be closely monitored to ensure that projects remain on-track and that any potential problems can be identified and remedied at an early stage. The deployment of King?s based portfolio support staff will benefit both King?s and the MRC. King?s based portfolio support staff will assist applicants in the drafting of their translational proposals and so improve the quality and relevance of applications. Portfolio support staff will therefore benefit both King?s and the MRC by increasing the number of high quality DPFS projects and by maximizing the probability that they achieve their goals or are terminated at an appropriate early stage. A devolved portfolio will also reduce the burden on MRC Head Office of overseeing projects at King?s.

应用基础医学研究成果改善患者的健康状况是现代医学的主要目标。为了做到这一点，我们必须确定最好的科学思想，这些思想可以导致新疗法的发展，改进疾病诊断和预测不同治疗效果的方法。将这些基础发现发展或转化为应用（转化研究）是MRC的目标。发展路径资助计划（DPFS）。国王?伦敦学院致力于翻译研究，并在人员和设施方面投入了大量资金，以促进和支持我们在这一领域的活动。鉴于国王学院对转化研究的浓厚兴趣？因此，我们预期我们的科学家会向该计划提交大量申请，并会有相当数量的获资助项目运作。DPFS项目有内置的里程碑，可以用来衡量研究的进展，如果没有达到预期的进展，项目可以停止的Go/No Go点。大多数学术科学家在这种转化的、里程碑式的项目上经验有限。我们正在为下放的投资组合支持请求基础资源，以招募一名投资组合支持人员来管理国王？S申请及资助项目。King的投资组合支持人员？我们将能够在申请DPFS拨款之前与科学家进行互动，以确保提案具有强大的转化潜力，具有现实的里程碑和决策点。当地的工作人员会监督国王吗？协助科学家进行项目管理。这种监督将使每个项目的进展情况得到密切监测，以确保项目保持在正轨上，并能及早发现和纠正任何潜在的问题。金的部署？总部位于美国的投资组合支持人员将使King？s和MRC。国王?基于S的投资组合支持人员将协助申请人起草他们的翻译建议，从而提高申请的质量和相关性。因此，投资组合支持人员将使King？通过增加高质量DPFS项目的数量，并通过最大限度地提高它们实现目标或在适当的早期阶段终止的可能性，来实现这一目标。下放的投资组合也将减轻MRC总部在金斯监督项目的负担。