QUAlitative Research in Trials - the QUART Study

试验中的定性研究 - QUART 研究

• 批准号: G0901335/1
• 负责人: Alicia O'Cathain
• 金额: $ 30.13万
• 依托单位: University of Sheffield
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2010
• 资助国家: 英国
• 起止时间: 2010 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G0901335%2F1
• 关键词: QUAlitative; Research; Trials; QUART; Study

The way in which researchers look at the effectiveness of health care has changed over time. They are more likely to use qualitative methods (interviews, focus groups, observation) with randomised controlled trials (RCTs). For example interviews with patients might be used to help develop treatments and services which fully meet their needs, explore how treatments are used by both patients and staff in the real world, or help to interpret the study results. In practice, researchers may be using qualitative research to ‘add value to RCTs‘, or as an additional piece of research focused solely on the disease or patient group. The use of qualitative research methods requires closer inspection if we are to understand the benefits that a shift to a mixed methods approach (this combination of qualitative methods and RCTs) might offer. We will address the question ‘what work do qualitative methods do in RCTs?‘Examples of the use of qualitative methods in or alongside trials will be identified from two sources. First, we will undertake a systematic search of key databases to find journal articles that report the use of qualitative methods in the context of an RCT. Second, we will search databases of studies to find reports and protocols that use qualitative methods. This latter approach will identify the most up to date approach taken to qualitative methods in RCTs. Initial searches suggest that we will find around 100-200 relevant studies.We will extract information from the articles, proposals and reports to describe and categorise the different ways in which qualitative methods are currently used. The study will provide examples of the successful use of qualitative methods in RCTs; raise awareness of how qualitative methods are used to assist (or not) the evidence base produced by trials; and identify ways in which researchers can best use qualitative methods within trials. The overall aim is to inform how we do research to improve health care.

随着时间的推移，研究人员看待医疗保健有效性的方式发生了变化。他们更可能使用定性方法（访谈，焦点小组，观察）与随机对照试验（RCT）。例如，与患者的访谈可能被用来帮助开发完全满足他们需求的治疗和服务，探索患者和工作人员在真实的世界中如何使用治疗，或帮助解释研究结果。在实践中，研究人员可能会使用定性研究来“增加RCT的价值”，或者作为仅关注疾病或患者群体的额外研究。如果我们要理解转向混合方法（定性方法和RCT的结合）可能带来的好处，就需要对定性研究方法的使用进行更仔细的检查。我们将讨论这样一个问题：“定性方法在RCT中做什么工作？”将从两个来源确定在试验中或与试验同时使用定性方法的例子。首先，我们将对关键数据库进行系统检索，以找到报告在RCT背景下使用定性方法的期刊文章。其次，我们将搜索研究数据库，以找到使用定性方法的报告和协议。后一种方法将确定RCT中定性方法的最新方法。初步搜索表明，我们将找到大约100-200项相关研究。我们将从文章，提案和报告中提取信息，以描述和分类目前使用定性方法的不同方式。这项研究将提供在随机对照试验中成功使用定性方法的例子;提高人们对如何使用定性方法来帮助（或不帮助）试验产生的证据基础的认识;并确定研究人员在试验中最好地使用定性方法的方法。总体目标是告知我们如何进行研究以改善医疗保健。