MRC Network of UK Brain Banks: Support for the Coordinating Centre

英国脑库 MRC 网络：对协调中心的支持

• 批准号: G0901945/1
• 负责人: James Ironside
• 金额: $ 52.3万
• 依托单位: University of Edinburgh
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2010
• 资助国家: 英国
• 起止时间: 2010 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G0901945%2F1
• 关键词: MRC; Network; UK; Brain; Banks

The UK is facing a major challenge to health services, carers and the economy in dealing with the increasing numbers of individuals who are suffering from progressive neurological diseases such as Alzheimer?s disease and Parkinson?s disease. As the population ages, increasing numbers of individuals are likely to develop these diseases and this places a high priority on improving our knowledge of these diseases, the mechanisms through which the brain is damaged, and identifying new opportunities for treatment and for better diagnostic tests in living patients. The aim of the Network of UK brain banks is to support this vital research by making brain tissue samples of the highest quality available to researchers in the UK. The Network will also address the shortage of normal tissue samples that are required as control material for the disease tissue samples. The Network will allow its members to work together in a more co-ordinated way, resulting in a more flexible and cost-efficient operation. The benefits of the Network for researchers will also be increased by creating a website that allows easy access to information on the nature and type of brain tissue samples stored in the various banks across the UK. The Network will also use the website to provide new information to potential brain tissue donors, and will direct these towards the most appropriate donor scheme operating at one of the banks in the Network. This project will therefore enable more research, not just into Alzheimer?s disease but into a wider range of neurological and neuropsychiatric diseases, such as motor neurone disease and schizophrenia. These devastating disorders represent a major challenge for 21st century health care and have been identified as a priority area for the NHS. This Network will support the excellent research already being undertaken in the UK, and allow it to develop further at a faster rate than currently is possible. The Network will also provide a focus for the general public in understanding more about brain tissue donation, and this increased awareness will also help support research in the UK.

英国正面临着一个重大挑战，卫生服务，照顾者和经济在处理越来越多的人谁是患有进行性神经系统疾病，如阿尔茨海默氏症？帕金森病与帕金森？的疾病。随着人口老龄化，越来越多的人可能会患上这些疾病，这就要求我们高度重视提高对这些疾病的认识，了解大脑受损的机制，并确定新的治疗机会和对活着的病人进行更好的诊断测试。英国脑库网络的目标是通过为英国的研究人员提供最高质量的脑组织样本来支持这一重要研究。该网络还将解决作为疾病组织样本对照材料所需的正常组织样本短缺问题。该网络将使其成员能够以更协调的方式共同努力，从而使业务更加灵活和具有成本效益。该网络为研究人员带来的好处还将通过创建一个网站来增加，该网站允许轻松访问存储在英国各地银行的脑组织样本的性质和类型的信息。该网络还将利用该网站向潜在的脑组织捐赠者提供新的信息，并将这些信息引导到在该网络的一个库中运作的最合适的捐赠计划。因此，该项目将促进更多研究，而不仅仅是阿尔茨海默病？但是，它也可以用于更广泛的神经和神经精神疾病，如运动神经元疾病和精神分裂症。这些毁灭性的疾病代表了21世纪世纪卫生保健的一个重大挑战，并已被确定为国民保健服务的优先领域。该网络将支持英国已经开展的优秀研究，并使其以比目前更快的速度进一步发展。该网络还将为公众提供一个关注点，让他们更多地了解脑组织捐赠，这种意识的提高也将有助于支持英国的研究。