Understanding how cells trigger mitosis

了解细胞如何触发有丝分裂

• 批准号: G1000818/1
• 负责人: Jonathon Pines
• 金额: $ 234.5万
• 依托单位: University of Cambridge
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2011
• 资助国家: 英国
• 起止时间: 2011 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G1000818%2F1
• 关键词: Understanding; how; cells; trigger; mitosis

We hope to discover exactly how the cell makes the decision to divide into two. This is a crucial decision because when it goes wrong the two daughter cells that are formed can go on to cause cancer, or become resistant to current anti-cancer drugs. In the course of this research we hope to uncover new targets for anti-cancer drugs and to identify ways to make current anti-cancer drugs much more effective.

我们希望能确切地发现细胞是如何决定一分为二的。这是一个至关重要的决定，因为当它出错时，形成的两个子细胞可能会继续导致癌症，或者对目前的抗癌药物产生抗药性。在这项研究的过程中，我们希望发现抗癌药物的新靶点，并确定使现有抗癌药物更有效的方法。