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Understanding how cells trigger mitosis

Understanding how cells trigger mitosis
了解细胞如何触发有丝分裂
批准号:
G1000818/1
负责人:
Jonathon Pines
金额:
$234.5万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2011
资助国家:
英国
项目状态:
已结题
起止时间:
2011 至 --

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中文摘要
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英文摘要
We hope to discover exactly how the cell makes the decision to divide into two. This is a crucial decision because when it goes wrong the two daughter cells that are formed can go on to cause cancer, or become resistant to current anti-cancer drugs. In the course of this research we hope to uncover new targets for anti-cancer drugs and to identify ways to make current anti-cancer drugs much more effective.
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Smart acquisition and data reduction for light-sheet microscopy of the cell cycle
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How is the Spindle Assembly Checkpoint turned off?
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Understanding mitosis using real time analysis of mitotic protein kinase activity
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    2008
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How does the spindle checkpoint convert Cdc20 into an APC/C substrate?
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