To investigate the performance of scanning laser polarimetry and scanning laser ophthalmoscopy in glaucoma case finding

探讨扫描激光偏振测定法和扫描激光检眼镜在青光眼病例发现中的性能

• 批准号: G1001939/1
• 负责人: Michelle Chan
• 金额: $ 28.09万
• 依托单位: University College London
• 依托单位国家: 英国
• 项目类别: Fellowship
• 财政年份: 2011
• 资助国家: 英国
• 起止时间: 2011 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G1001939%2F1
• 关键词: investigate; performance; scanning; laser; polarimetry

Glaucoma is an eye disease in which the optic nerve is damaged, causing loss of vision. It is the commonest cause of irreversible blindness worldwide. It produces no symptoms until advanced, but abnormalities are detectable on examination from an early stage. However, there is no proven rapid test or combination of tests to screen for glaucoma. In the UK, many people undergo eye pressure measurement by an optician, but studies show that round 50% of glaucoma remains undetected in the community. Scanning laser polarimetry (GDx) and Heidelberg Retinal Tomography (HRT) are imaging devices used to diagnose & monitor glaucoma. Respectively, they measure the thickness of the nerve fibre layer near the optic nerve, and analyse the contour of the optic nerve with computer software. They have the advantage of being fast, objective, reproducible and can be carried out by a technician.This research aims to evaluate the combined use of GDx and HRT as screening tools for glaucoma. It will analyse existing data on residents of Norfolk. Many have undergone ophthalmological examination to determine if they have glaucoma or not. The practical application of the findings could be a more robust screening method, being able to identify those with glaucoma at an early stage.

青光眼是一种视神经受损的眼部疾病，导致视力丧失。它是全世界不可逆失明的最常见原因。它直到晚期才产生症状，但在早期阶段检查时可发现异常。然而，目前还没有经过验证的快速测试或测试组合来筛查青光眼。在英国，许多人接受眼镜商的眼压测量，但研究表明，大约50%的青光眼在社区中仍未被发现。扫描激光偏振仪（GDx）和海德堡视网膜断层扫描仪（HRT）是用于诊断和监测青光眼的成像设备。他们分别测量视神经附近的神经纤维层厚度，并用计算机软件分析视神经的轮廓。它们具有快速、客观、重复性好、可由技术人员进行等优点，本研究旨在评估GDx和HRT联合使用作为青光眼筛查工具的价值。它将分析诺福克居民的现有数据。许多人接受了眼科检查，以确定他们是否患有青光眼。这些发现的实际应用可能是一种更强大的筛查方法，能够在早期阶段识别青光眼患者。