Cognitive behavioural therapy (CBT) as an early intervention for PTSD in youth: preliminary efficacy and mechanisms of a

认知行为疗法（CBT）作为青少年创伤后应激障碍（PTSD）的早期干预：初步疗效和机制

• 批准号: MC_EX_G0802821
• 负责人: Richard Meiser-Stedman
• 金额: $ 62.6万
• 依托单位: MRC Cognition and Brain Sciences Unit
• 依托单位国家: 英国
• 项目类别: Fellowship
• 财政年份: 2009
• 资助国家: 英国
• 起止时间: 2009 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MC_EX_G0802821
• 关键词: Cognitive; behavioural; therapy; CBT; early

Following horrific or life threatening events (e.g. serious accidents, violence, or natural disasters) children and adolescents can, like adults, develop post-traumatic stress disorder (PTSD). PTSD is a serious anxiety disorder that can cause major disruption to an individual's functioning, and if left untreated can persist for years or even decades. Recent research suggests that severe early PTSD symptoms put youth at high risk of developing chronic PTSD. Furthermore, it has been shown that that the development of PTSD in this age group is related to certain psychological processes, i.e. their memories of the trauma, and particular ways of thinking about and coping with the trauma. This understanding has led to the development of a psychological treatment for PTSD in youth. This treatment, cognitive behavioural therapy (CBT), has been shown to successfully treat chronic PTSD in children and adolescents. The proposed research seeks to examine whether CBT might be an effective treatment for PTSD in the first few months following a trauma, and investigate in greater detail which psychological and biological processes lead to the development of early PTSD in young people. This research will inform how PTSD in young people can be best treated at an early stage.

在可怕或威胁生命的事件（例如严重事故，暴力或自然灾害）之后，儿童和青少年可能会像成年人一样发展创伤后应激障碍（PTSD）。创伤后应激障碍是一种严重的焦虑症，可能会对个体的功能造成重大破坏，如果不加以治疗，可能会持续数年甚至数十年。最近的研究表明，严重的早期创伤后应激障碍症状使年轻人处于发展慢性创伤后应激障碍的高风险之中。此外，已经表明，这个年龄组的PTSD的发展与某些心理过程有关，即他们对创伤的记忆，以及思考和应对创伤的特定方式。这种理解导致了青少年PTSD心理治疗的发展。这种治疗，认知行为疗法（CBT），已被证明可以成功治疗儿童和青少年的慢性PTSD。这项拟议中的研究旨在研究CBT是否可能是创伤后最初几个月内PTSD的有效治疗方法，并更详细地调查哪些心理和生物过程导致年轻人早期PTSD的发展。这项研究将告知如何在早期阶段最好地治疗年轻人的PTSD。

项目成果

The Dutch version of the Child Posttraumatic Cognitions Inventory: validation in a clinical sample and a school sample.

• DOI: 10.3402/ejpt.v6.26362
• 发表时间: 2015
• 期刊: European journal of psychotraumatology
• 影响因子: 5
• 作者: Diehle J;de Roos C;Meiser-Stedman R;Boer F;Lindauer RJ
• 通讯作者: Lindauer RJ

Cohort profile: mental health following extreme trauma in a northern Ugandan cohort of War-Affected Youth Study (The WAYS Study).

• DOI: 10.1186/2193-1801-2-300
• 发表时间: 2013-12
• 期刊: SpringerPlus
• 作者: Amone-P'olak K;Jones PB;Abbott R;Meiser-Stedman R;Ovuga E;Croudace TJ
• 通讯作者: Croudace TJ

War experiences, general functioning and barriers to care among former child soldiers in Northern Uganda: the WAYS study.

• DOI: 10.1093/pubmed/fdt126
• 发表时间: 2014-12
• 期刊: Journal of public health (Oxford, England)
• 作者: Amone-P'Olak K;Jones P;Meiser-Stedman R;Abbott R;Ayella-Ataro PS;Amone J;Ovuga E
• 通讯作者: Ovuga E

Genome-wide association study of response to cognitive-behavioural therapy in children with anxiety disorders.

• DOI: 10.1192/bjp.bp.115.168229
• 发表时间: 2016-09
• 期刊: The British journal of psychiatry : the journal of mental science
• 作者: Coleman JR;Lester KJ;Keers R;Roberts S;Curtis C;Arendt K;Bögels S;Cooper P;Creswell C;Dalgleish T;Hartman CA;Heiervang ER;Hötzel K;Hudson JL;In-Albon T;Lavallee K;Lyneham HJ;Marin CE;Meiser-Stedman R;Morris T;Nauta MH;Rapee RM;Schneider S;Schneider SC;Silverman WK;Thastum M;Thirlwall K;Waite P;Wergeland GJ;Breen G;Eley TC
• 通讯作者: Eley TC

Trauma-focused cognitive behaviour therapy versus treatment as usual for post traumatic stress disorder (PTSD) in young children aged 3 to 8 years: study protocol for a randomised controlled trial.

• DOI: 10.1186/s13063-015-0632-2
• 发表时间: 2015-03-25
• 期刊: Trials
• 影响因子: 2.5
• 作者: Dalgleish T;Goodall B;Chadwick I;Werner-Seidler A;McKinnon A;Morant N;Schweizer S;Panesar I;Humphrey A;Watson P;Lafortune L;Smith P;Meiser-Stedman R
• 通讯作者: Meiser-Stedman R