Wellcome Trust MRC Cambridge Stem Cell Institute
Wellcome Trust MRC Cambridge Stem Cell Institute
批准号:
MC_PC_12009
负责人:
金额:
$391.7万
依托单位:
依托单位国家:
英国
项目类别:
Intramural
财政年份:
2012
资助国家:
英国
项目状态:
已结题
起止时间:
2012 至 --
中文摘要
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英文摘要
Wellcome Trust MRC Cambridge Stem Cell InstituteDirector: Professor Austin Smith, University of CambridgeStem cell science is providing a stream of new knowledge about how our bodies are made and maintained. This research brings the promise that better understanding of stem cells will lead to future medical applications. Treatments may come through several routes. First, human stem cells grown in the laboratory can be used to produce experimental models of diseased tissues and to test therapeutic drugs. Second, some disorders, including forms of cancer, involve abnormal behaviour of stem cells. As we learn how to control stem cells it may become possible to correct these faults. Third, finding how to prevent a decline in numbers and activity of stem cells may help to maintain health during ageing. Finally, stem cells could be used to renew damaged tissues and replace missing cells in certain disorders.The Cambridge Stem Cell Institute is being formed to explore and define the properties of stem cells and establish their true medical potential. Leading research scientists, technology specialists and doctors will work side by side to create a world-leading centre of excellence in stem cell biology and medicine. The Institute will also collaborate with bioindustry and will provide high level training for young researchers from around the world.
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Prediction of acute myeloid leukaemia risk in healthy individuals.
在健康个体中预测急性髓样白血病的风险。
DOI:
10.1038/s41586-018-0317-6
发表时间:
2018-07
期刊:
Nature
影响因子:
64.8
作者:
[Abelson S, Collord G, Ng SWK, Weissbrod O, Mendelson Cohen N, Niemeyer E, Barda N, Zuzarte PC, Heisler L, Sundaravadanam Y, Luben R, Hayat S, Wang TT, Zhao Z, Cirlan I, Pugh TJ, Soave D, Ng K, Latimer C, Hardy C, Raine K, Jones D, Hoult D, Britten A, McPherson JD, Johansson M, Mbabaali F, Eagles J, Miller JK, Pasternack D, Timms L, Krzyzanowski P, Awadalla P, Costa R, Segal E, Bratman SV, Beer P, Behjati S, Martincorena I, Wang JCY, Bowles KM, Quirós JR, Karakatsani A, La Vecchia C, Trichopoulou A, Salamanca-Fernández E, Huerta JM, Barricarte A, Travis RC, Tumino R, Masala G, Boeing H, Panico S, Kaaks R, Krämer A, Sieri S, Riboli E, Vineis P, Foll M, McKay J, Polidoro S, Sala N, Khaw KT, Vermeulen R, Campbell PJ, Papaemmanuil E, Minden MD, Tanay A, Balicer RD, Wareham NJ, Gerstung M, Dick JE, Brennan P, Vassiliou GS, Shlush LI]
通讯作者:
Shlush LI
Oesophageal Stem Cells and Cancer.
食管干细胞和癌症。
DOI:
10.1007/978-3-319-69194-7_10
发表时间:
2017
期刊:
Advances in experimental medicine and biology
影响因子:
--
作者:
[Alcolea MP]
通讯作者:
Alcolea MP
DOI:
10.1038/s41598-020-73802-w
发表时间:
2020-10-07
期刊:
Scientific reports
影响因子:
4.6
作者:
[Aalders J, Léger L, Van der Meeren L, Van den Vreken N, Skirtach AG, Sinha S, De Backer J, van Hengel J]
通讯作者:
van Hengel J
DOI:
10.1158/1541-7786.mcr-20-0693
发表时间:
2020-12
期刊:
Molecular cancer research : MCR
影响因子:
--
作者:
[Ali FR, Marcos D, Chernukhin I, Woods LM, Parkinson LM, Wylie LA, Papkovskaia TD, Davies JD, Carroll JS, Philpott A]
通讯作者:
Philpott A
Prediction of acute myeloid leukaemia risk in healthy individuals
健康个体急性髓性白血病风险的预测
DOI:
10.17863/cam.30393
发表时间:
2018
期刊:
影响因子:
--
作者:
[Abelson S]
通讯作者:
Abelson S
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