Strategies to reduce pre-treatment loss to follow-up and improve successful patient outcomes in a TB hotspot

减少治疗前随访损失并改善结核病热点地区患者成功治疗结果的策略

• 批准号: MC_PC_16023
• 负责人: Shabir Madhi
• 金额: $ 48.07万
• 依托单位: National Health Laboratory Service
• 依托单位国家: 英国
• 项目类别: Intramural
• 财政年份: 2016
• 资助国家: 英国
• 起止时间: 2016 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MC_PC_16023
• 关键词: Strategies; reduce; pre; treatment; loss

The direct and indirect costs to individuals and households of accessing care are a critical barrier to TB treatment initiation and completion with poorer households incurring greater costs. While the associations between poverty and TB infection, TB disease and TB treatment outcomes are well documented there have been very few studies of economic interventions to improve TB outcomes. Other important barriers to successful TB treatment include health system weaknesses and unproductive patient-provider interactions resulting in limited patient motivation and understanding. In this study we will explore the effects of two interventions: 1) counselling patients before and after a TB test is performed and 2) giving patients limited financial support on the rates of TB treatment initiation and completion.

个人和家庭获得医疗服务的直接和间接费用是开始和完成结核病治疗的关键障碍，较贫穷的家庭承担的费用更高。虽然贫困与结核病感染、结核病和结核病治疗结果之间的关联有很好的文献记载，但很少有关于改善结核病结果的经济干预的研究。成功治疗结核病的其他重要障碍包括卫生系统薄弱和无效的患者与提供者互动，导致患者动机和理解有限。在这项研究中，我们将探讨两种干预措施的影响：1)在进行结核病检测之前和之后向患者提供咨询，以及2)向患者提供有限的财政支持，以提高结核病治疗的开始和完成率。

项目成果

The impact of HIV infection on tuberculosis transmission in a country with low tuberculosis incidence: a national retrospective study using molecular epidemiology.

• DOI: 10.1186/s12916-020-01849-7
• 发表时间: 2020-12-14
• 期刊: BMC medicine
• 影响因子: 9.3
• 作者: Winter JR;Smith CJ;Davidson JA;Lalor MK;Delpech V;Abubakar I;Stagg HR
• 通讯作者: Stagg HR