Accelerating Product Development in Global Health

加速全球健康领域的产品开发

• 批准号: MC_PC_16078
• 负责人: Stephen Ward
• 金额: $ 15.93万
• 依托单位: Liverpool School of Tropical Medicine
• 依托单位国家: 英国
• 项目类别: Intramural
• 财政年份: 2017
• 资助国家: 英国
• 起止时间: 2017 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MC_PC_16078
• 关键词: Accelerating; Product; Development; Global; Health

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

Glycan-independent binding and internalization of human IgM to FCMR, its cognate cellular receptor.

人 IgM 与其同源细胞受体 FCMR 的独立于聚糖的结合和内化

• DOI: 10.1038/srep42989
• 发表时间: 2017-02-23
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Lloyd KA;Wang J;Urban BC;Czajkowsky DM;Pleass RJ
• 通讯作者: Pleass RJ

Choice of host cell line is essential for the functional glycosylation of the fragment crystallizable (Fc) region of human IgG1 inhibitors of influenza B viruses

• DOI: 10.1101/719849
• 发表时间: 2019-07
• 期刊: bioRxiv
• 作者: P. Blundell;Dongli Lu;A. Dell;S. Haslam;R. Pleass

Engineering the fragment crystallizable (Fc) region of human IgG1 multimers and monomers to fine-tune interactions with sialic acid-dependent receptors.

• DOI: 10.1074/jbc.m117.795047
• 发表时间: 2017-08-04
• 期刊: The Journal of biological chemistry
• 作者: Blundell PA;Le NPL;Allen J;Watanabe Y;Pleass RJ
• 通讯作者: Pleass RJ

A Method to Detect the Binding of Hyper-Glycosylated Fragment Crystallizable (Fc) Region of Human IgG1 to Glycan Receptors.

一种检测人 IgG1 高糖基化片段可结晶 (Fc) 区域与聚糖受体结合的方法。

• DOI: 10.1007/978-1-4939-8958-4_20
• 发表时间: 2019
• 期刊: Methods in molecular biology (Clifton, N.J.)
• 作者: Blundell P