A global registry of women affected by COVID-19 in pregnancy, understanding natural history to guide treatment and prevention

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The current coronavirus outbreak (COVID-19) is growing in magnitude and will affect hundreds of pregnant women globally. MERS, SARS, and other coronovirus infectionscause more severe illness in pregnant women than non-pregnant women, with higher rates of deaths, pregnancy loss, premature births and small-for-dates babies.There have been case reports of 18 women affected by COVID-19 in the later third of their pregnancy. There is a lack of information on the effect of COVID-19 at all stages of pregnancy e.g. early pregnancy and its effect on mothers’ and babies’ health before and after delivery.This study will gather information from around the world of COVID-19 infection during pregnancy to inform treatment and how to prevent spread.We will set up a database (register) of women affected by COVID-19 in pregnancy. Cases will be added by collaborators across Europe, China, Hong Kong and the USA. Information about the women, their pregnancies and babies will be entered by healthcare professionals into a secure web page.Weekly reports from registery will be published online. This database of reported cases with detailed pregnancy outcomes will allow healthcare professionals, researchers and policy makers to plan prevention and treatments in this outbreak, and in the future.