Strategic Alliance Funding: MRC Weatherall Institute of Molecular Medicine (WIMM) at the University of Oxford 22-27

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Modern biomedical research is driven by advanced technologies, the generation of massive multidimensional datasets and advanced computational analysis is critical for their use. Similarly, research institutes must be able to adopt cutting-edge experimental approaches, such as single cell technologies. However, the huge complexity of these data puts even more pressure on computational biology and machine learning approaches.In this proposal we laid out our strategic plan to redevelop and focus the computational infrastructure of the WIMM to meet these challenges. To build on existing expertise, to centralise and build synergy between these expert groups. We have made key hires, from diverse fields such as mathematics and computer science, with such expertise. We are developing critical computational talent, by promoting and mentoring young computational scientists from the WIMM. A critical goal for us is to expand and democratise these skills in the WIMM, through new training programmes, in particular with students. We have now completely modernised our High Performance Cluster in both speed and capacity and instituted a sustainable charging business model for long term stability.