Determining the causes of congenital malformation

确定先天性畸形的原因

• 批准号: nhmrc : 1042002
• 负责人: Prof Sally Dunwoodie
• 金额: $ 45.79万
• 依托单位: Victor Chang Cardiac Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/determining-causes-congenital-malformation/111427
• 关键词: Determining; causes; congenital; malformation

Birth defects are present in 3% of live births and account for some of the 78% of fetuses lost before birth. The causes of these defects are largely unknown. Some are due to genetic factors, some to environmental stresses, and others to a combination of genetic and environmental influences on fetal development. This research aims to identify the genetic and environmental factors that cause birth defects with the anticipation that the occurrence of birth defects may be reduced.

出生缺陷存在于3%的活产婴儿中，占出生前丢失的胎儿的78%。这些缺陷的原因在很大程度上是未知的。有些是由于遗传因素，有些是由于环境压力，还有一些是由于遗传和环境对胎儿发育的影响。本研究的目的是确定导致出生缺陷的遗传和环境因素，以期减少出生缺陷的发生。