Determining the cellular mechanism underlying diffuse axonal injury following brain trauma

确定脑外伤后弥漫性轴突损伤的细胞机制

• 批准号: nhmrc : 544925
• 负责人: Prof James Vickers
• 金额: $ 26.73万
• 依托单位: Menzies Institute for Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/determining-cellular-mechanism-brain-trauma/100867
• 关键词: Determining; cellular; mechanism; underlying; diffuse

Traumatic head injury causes transient stretch injury to the nerve cell processes within the brain. This leads to a poorly understood series of cellular changes within nerve cells which may ultimately lead to their breakage and subsequent neurological disability. This project seeks to understand how this nerve cell damage forms, and explores new potential interventions which may protect the brain.

创伤性头部损伤导致脑内神经细胞突起的短暂牵拉损伤。这导致神经细胞内的一系列细胞变化知之甚少，最终可能导致其断裂和随后的神经功能障碍。该项目旨在了解这种神经细胞损伤是如何形成的，并探索可能保护大脑的新的潜在干预措施。