Muslim Communities Learning About Second-hand Smoke - MCLASS pilot cluster randomised controlled trial

穆斯林社区了解二手烟 - MCLASS 试点集群随机对照试验

• 批准号: MR/J000248/1
• 负责人: Kamran Siddiqi
• 金额: $ 41.2万
• 依托单位: University of York
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2012
• 资助国家: 英国
• 起止时间: 2012 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MR%2FJ000248%2F1
• 关键词: Muslim; Communities; Learning; About; Second

In the UK, 40% of Bangladeshi and 29% of Pakistani men smoke cigarettes regularly compared to the national average of 24%. Second-hand smoking (SHS) is also common in their households, which is a serious health hazard to non-smokers, especially children.Smoking restrictions in households reduces children's exposure to SHS. In addition, smokers are more likely to quit and young people are less likely to initiate smoking if living in households with smoking restrictions.Our aims are to identify effective ways of protecting children and non-smoking adults from SHS, and to reduce uptake of smoking and improve smoking quit rates in deprived communities in the UK. We carried out a preliminary study of 'Smoke Free Homes' using three approaches (schools, healthcare organizations and community organizations, in particular mosques) in a locality with a significant Pakistani-origin population. However, the study design precluded reliable inferences about its effectiveness. We are now embarking on to establish the effectiveness of 'Smoke Free Homes' delivered through each of these three routes. We have secured research grants to test two of these approaches (school & healthcare). This application pursuing the community-faith leaders approach aims to complement the existing strands of work and will lead to a definitive trial application. In order to establish the effectiveness of this approach, a cluster-randomized trial is needed. However, prior to a large (and expensive) definitive study we plan to carry out a pilot trial. A pilot trial of 'Smoke Free Homes', will inform the design of a definitive trial in future. Our research objectives include: establishing the number of clusters (mosques) and the size of each cluster (participants) required for the main trial, ascertain recruitment and loss to follow-up rates, and other statistical requirements (effect size and intra-class coefficient); establishing feasibility, acceptability and resource requirements for delivering the intervention and assessing outcomes; and understanding the extent to which 'Smoke Free Homes' can be integrated into mosques' routine.We will carryout a cluster randomised controlled pilot trial of 'Smoke Free Homes' over 24 months with an embedded preliminary health economic and a qualitative study. The trial will be carried out in fourteen mosques, which host communal prayers, convene study circles for women and have regular Qur'an classes for children. We developed a toolkit titled "Smoke Free Homes: A toolkit for Muslim religious teachers" which consists of a series of fact sheets detailing key information on smoking, SHS and 'Smoke Free Homes', a series of activities through which the key information can be disseminated, and tools to plan and monitor these activities. We have also prepared a training package to enable three key groups of Muslim religious leaders i.e. Imams who mainly interact with adult males, Qur'an teachers who mainly interact with children and women circle leaders to use this toolkit with their respective congregations.No intervention will be carried out in the control arms until after the trial. From each mosque, we aim to recruit at least 50 households with at least one adult resident who smokes cigarette and at least one child or a non-smoking adult. All outcomes will be measured before and after the intervention in each arm of the study. We will measure salivary cotinine levels in non-smokers in the households as the primary outcome. It is a widely recognized method for detecting both active and passive smoking. Secondary outcomes include assessment of smoking restrictions at home, smoking status of adults' and their intention to quit, and family health service use. A multidisciplinary team with the engagement of relevant stakeholders will lead the research. Research findings will be published and presented in peer-reviewed journals and scientific meetings respectively.

在英国，40%的孟加拉国男性和29%的巴基斯坦男性经常吸烟，而全国平均水平为24%。二手烟（SHS）在他们的家庭中也很常见，这对不吸烟的人，尤其是儿童，是一个严重的健康危害。在家庭中限制吸烟可减少儿童接触二手烟。此外，如果生活在有吸烟限制的家庭中，吸烟者戒烟的可能性更大，年轻人开始吸烟的可能性更小。我们的目标是确定有效的方法来保护儿童和不吸烟的成年人免受二手烟的侵害，并减少吸烟的吸收，提高英国贫困社区的吸烟率。我们在一个拥有大量巴基斯坦裔人口的地区，采用三种方法（学校、医疗机构和社区组织，特别是清真寺）对“无烟家园”进行了初步研究。然而，研究设计排除了对其有效性的可靠推断。我们现在正着手通过这三条路线来确定“无烟家园”的有效性。我们已经获得了研究资助，以测试其中两种方法（学校和医疗保健）。这项采用社区信仰领袖方法的申请旨在补充现有的工作，并将导致最终的试用申请。为了确定该方法的有效性，需要进行集群随机试验。然而，在进行大规模（且昂贵）的确定研究之前，我们计划进行试点试验。“无烟家庭”的试点试验将为未来最终试验的设计提供信息。我们的研究目标包括：确定主要试验所需的组群（清真寺）的数量和每个组群（参与者）的大小，确定招募率和随访率的损失，以及其他统计要求（效应大小和组内系数）；确定实施干预措施的可行性、可接受性和资源需求，并评估结果；以及了解“无烟之家”在多大程度上可以融入清真寺的日常生活。我们将开展一项为期24个月的“无烟家庭”随机对照试验，并进行初步健康经济和定性研究。这项试验将在14座清真寺进行，这些清真寺主持集体祈祷，为妇女召集学习班，并定期为儿童开设古兰经课程。我们制作了一套名为“无烟家园：穆斯林宗教教师的工具包”的工具，其中包括一系列关于吸烟、二手烟和“无烟家园”的重要信息的实况介绍，一系列可传播这些重要信息的活动，以及策划和监督这些活动的工具。我们还准备了一个培训包，使三个主要的穆斯林宗教领袖群体，即主要与成年男性互动的伊玛目、主要与儿童互动的古兰经教师和妇女圈子领袖，能够在各自的会众中使用这个工具包。在试验结束之前，不会对对照组进行干预。从每个清真寺，我们的目标是招募至少50个家庭，其中至少有一个成年居民吸烟，至少有一个儿童或不吸烟的成年人。所有结果将在研究的每个组的干预前后进行测量。我们将测量家庭中非吸烟者的唾液可替宁水平作为主要结果。这是一种被广泛认可的检测主动吸烟和被动吸烟的方法。次要结局包括评估家庭吸烟限制、成人吸烟状况及其戒烟意图，以及家庭卫生服务使用情况。一个由相关利益攸关方参与的多学科小组将领导这项研究。研究成果将分别在同行评议的期刊和科学会议上发表和介绍。

项目成果

Secondhand smoke exposure during pregnancy: a cross-sectional analysis of data from Demographic and Health Survey from 30 low-income and middle-income countries.

• DOI: 10.1136/tobaccocontrol-2018-054288
• 发表时间: 2019-07
• 期刊: TOBACCO CONTROL
• 影响因子: 5.2
• 作者: Reece, Sian;Morgan, Camille;Parascandola, Mark;Siddiqi, Kamran
• 通讯作者: Siddiqi, Kamran

Muslim communities learning about second-hand smoke (MCLASS): study protocol for a pilot cluster randomised controlled trial.

• DOI: 10.1186/1745-6215-14-295
• 发表时间: 2013-09-13
• 期刊: Trials
• 影响因子: 2.5
• 作者: Ainsworth H;Shah S;Ahmed F;Amos A;Cameron I;Fairhurst C;King R;Mir G;Parrott S;Sheikh A;Torgerson D;Thomson H;Siddiqi K
• 通讯作者: Siddiqi K

Involving mosques in health promotion programmes: a qualitative exploration of the MCLASS intervention on smoking in the home.

• DOI: 10.1093/her/cyx051
• 发表时间: 2017-08-01
• 期刊: Health education research
• 影响因子: 2.4
• 作者: King R;Warsi S;Amos A;Shah S;Mir G;Sheikh A;Siddiqi K
• 通讯作者: Siddiqi K

Muslim Communities Learning About Second-hand Smoke in Bangladesh (MCLASS II): study protocol for a cluster randomised controlled trial of a community-based smoke-free homes intervention, with or without Indoor Air Quality feedback

• DOI: 10.1186/s13063-018-3100-y
• 发表时间: 2019-01-05
• 期刊: TRIALS
• 影响因子: 2.5
• 作者: Mdege, Noreen;Fairhurst, Caroline;Siddiqi, Kamran
• 通讯作者: Siddiqi, Kamran