SINGLE-DOSE ORAL CIMETIDINE ON THE ACCURACY & PRECISION CREATININE CLEARANCE

单剂量口服西米替丁的准确性

• 批准号: 5218666
• 负责人: ARASB ATESHKADI
• 金额: --
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/5218666
• 关键词: biomarker; cimetidine; clearance rate; clinical research; creatinine; dosage; drug screening /evaluation; glomerular filtration rate; human subject; kidney pharmacology; oral administration

The goal of this study is to determine whether a single 1200-mg oral dose of cemetidine improves the precision and accuracy of creatinine clearance as a marker of glomerular filtration rate in patients with moderate-to-severe renal dysfunction.

这项研究的目标是确定单次1200毫克的口服剂量 西咪替丁可提高肌酐清除的精密度和准确度 作为慢性肾炎患者肾小球滤过率的指标 中度至重度肾功能不全。