Stratiform Optical Barcoding System for Cardiac Biomarkers: Towards Smart Computerised Clinical Prognosis of Cardiovascular Disease

心脏生物标志物的分层光学条形码系统：迈向心血管疾病的智能计算机化临床预后

• 批准号: DE140100549
• 负责人: A/Prof Abel Santos
• 金额: $ 26.08万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-01
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE140100549
• 关键词: Stratiform; Optical; Barcoding; System; Cardiac

This project involves the development of an innovative optical biosensing system combined with a sophisticated barcode system containing information for clinical diagnosis of cardiovascular disease. For the first time, this system will provide information on the amount and chemical structure of cardiac biomarkers at the same time by combining reflectometric interference and low resolution Raman spectroscopies. These optical signals will be converted into barcodes containing several levels of information, which will be at the base of this versatile point-of-care test. The obtained results will be implemented in a computerised database to improve current cardiac disease diagnosis.

该项目涉及开发一种创新的光学生物传感系统，结合包含心血管疾病临床诊断信息的复杂条形码系统。该系统将首次通过结合反射干涉和低分辨率拉曼光谱同时提供有关心脏生物标志物的数量和化学结构的信息。这些光信号将被转换成包含多个级别信息的条形码，这将是这种多功能即时检测的基础。所获得的结果将在计算机化数据库中实施，以改善当前的心脏病诊断。