SPECT CAMERA FOR MAMMOGRAPHY OF ISOLATED BREAST

这项提议是为了发展单光子的原型。 计算机断层扫描(SPECT)闪烁相机用于检测和 使用放射性示踪剂对乳腺肿瘤进行功能成像。这个 照相机将有一个固定的环形晶体探测器，以包围一个 下垂的乳房靠近并立体地成像，在 它的整体，与其他体内的放射性示踪剂浓度无关 器官。这架照相机的构造是由独特的 闪烁相机创新，在此的第一阶段开发 项目，该项目修改了光被 摄像机S光电倍增管。环形摄像机预计将提供 尽可能高的灵敏度、分辨率和肿瘤对比度 通过闪光照相的方法来实现。这些改进应该会导致 肿瘤的特异性和检测率比任何其他方法都要高 意思是。 建议的商业应用 由于其较高的特异性和可检测性，环状SPECT 孤立的乳房有可能与 或者在许多情况下替换现有的诊断方法。

This proposal is for the development of a prototype single photon computed tomography (SPECT) scintillation camera for the detection and functional imaging of breast tumors using radioactive tracers. The camera will have a stationary annular crystal detector, to surround a pendant breast in close proximity and image it three-dimensionally, in its entirety, independent of radiotracer concentrations in other body organs. The construction of this camera is made possible by unique scintillation camera innovations, developed during phase I of this project, which modify the way that light is directed and received by the camera s photomultipliers. The annular camera is expected to provide the highest possible sensitivity, resolution and tumor contrast that can be achieved by scintigraphic means. These improvements should result in higher specificity and detection of tumors than is possible by any other means. PROPOSED COMMERCIAL APPLICATION Because of its higher specificity and detectability, annular SPECT of an isolated breast has the potential of being used in conjunction with or replacing existing diagnostic methods in many instances.