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RENOVATION OF BIOCHEMISTRY LABORATORIES

生物化学实验室改造

基本信息

批准号：
6044583
负责人：
LESLIE A FLEMMING
金额：
$ 139.59万
依托单位：
OHIO UNIVERSITY ATHENS
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
起止时间：
1999-09-30 至 2002-09-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/6044583
关键词：
biomedical facility building /facility design /renovation

项目摘要

The research facility proposed by Ohio University will house seven biochemistry faculty members from the Department of Chemistry and Biochemistry. The expansion of the faculty in biochemistry is a result of a thorough review and restructuring of the department in 1994-95 in two areas of focus, the Chemistry of Biological Systems and Processes, and Chemical Analysis and Structure. The aim of the restructuring is to create a strategy to achieve national prominence in more focused arenas of research. Ohio University has invested in and committed to hiring new faculty, improving facilities, purchasing state-of-the-art instrumentation and enhancing services to the department to support increased research. The specific aim of the new facility is to design an open, flexible laboratory to encourage collaborations among the faculty and students. In addition to biochemistry students, the faculty in biochemistry participate through joint appointments and affiliations in the College of Osteopathic Medicine and the Edison Biotechnology Institute in the research training of students throughout the university including COE program is to increase the participation of the students in scientific research and this building is a significant addition to the research and training facilities for the university. The long-term goal is to raise the profile of the biochemistry program and make a significant contribution to the research and educational goals of the university.

由俄亥俄州大学提议的研究设施将容纳来自化学和生物化学系的七名生物化学教员。生物化学系的扩大是1994-95年在两个重点领域对该部门进行彻底审查和重组的结果，即生物系统和过程的化学以及化学分析和结构。重组的目的是制定一项战略，在重点更突出的研究领域实现全国领先地位。俄亥俄州大学已投资并致力于聘请新的教师，改善设施，购买国家的最先进的仪器和加强服务部门，以支持增加研究。新设施的具体目标是设计一个开放，灵活的实验室，以鼓励教师和学生之间的合作。除了生物化学的学生，生物化学的教师通过联合任命和附属机构在骨科医学学院和爱迪生生物技术研究所参与整个大学的学生的研究培训，包括COE计划是为了增加学生在科学研究中的参与，这座建筑是对大学研究和培训设施的重要补充。长期目标是提高生物化学计划的知名度，并为大学的研究和教育目标做出重大贡献。

项目成果

期刊论文数量（13）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

RNA drug discovery: Conformational restriction enhances specific modulation of the T-box riboswitch function.

DOI：
10.1016/j.bmc.2020.115696
发表时间：
2020-10-15
期刊：
Bioorganic & medicinal chemistry
影响因子：
3.5
作者：
Armstrong I;Aldhumani AH;Schopis JL;Fang F;Parsons E;Zeng C;Hossain MI;Bergmeier SC;Hines JV
通讯作者：
Hines JV

Arabinosylation Plays a Crucial Role in Extensin Cross-linking In Vitro.

DOI：
10.4137/bci.s31353
发表时间：
2015
期刊：
Biochemistry insights
影响因子：
0
作者：
Chen Y;Dong W;Tan L;Held MA;Kieliszewski MJ
通讯作者：
Kieliszewski MJ

Three β-Glucuronosyltransferase Genes Involved in Arabinogalactan Biosynthesis Function in Arabidopsis Growth and Development.

DOI：
10.3390/plants10061172
发表时间：
2021-06-09
期刊：
Plants (Basel, Switzerland)
影响因子：
0
作者：
Ajayi OO;Held MA;Showalter AM
通讯作者：
Showalter AM

The favorable kinetics and balance of nebivolol-stimulated nitric oxide and peroxynitrite release in human endothelial cells.

奈必洛尔刺激人内皮细胞中一氧化氮和过氧亚硝酸盐释放的有利动力学和平衡。

DOI：
10.1186/2050-6511-14-48
发表时间：
2013
期刊：
BMC pharmacology & toxicology
影响因子：
2.9
作者：
Mason,RPreston;Jacob,RobertF;Corbalan,JJose;Szczesny,Damian;Matysiak,Kinga;Malinski,Tadeusz
通讯作者：
Malinski,Tadeusz

Identification of the Abundant Hydroxyproline-Rich Glycoproteins in the Root Walls of Wild-Type Arabidopsis, an ext3 Mutant Line, and Its Phenotypic Revertant.