Durable, practical, effective and affordable formats for insecticide-treated eave baffles that protect households and suppress malaria transmission

耐用、实用、有效且价格实惠的经杀虫剂处理的屋檐挡板，可保护家庭并抑制疟疾传播

• 批准号: MR/P01691X/1
• 负责人: Gerry Killeen
• 金额: $ 19.27万
• 依托单位: Liverpool School of Tropical Medicine
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2017
• 资助国家: 英国
• 起止时间: 2017 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MR%2FP01691X%2F1
• 关键词: Durable; practical; effective; affordable; formats

Eave baffles (EBs) are a simple housing modification using widely-available netting materials, which can be treated with existing insecticide formulations. Treated EBs and window screens trap mosquitoes inside houses after they enter, and force them into lethal contact with insecticides when they attempt to exit again. Experimental prototypes of insecticide-treated EBs proved an equivalent or superior alternative to indoor residual spraying for killing malaria vectors in standardized experimental huts in southern Tanzania. EBs required >5 times less insecticide than IRS, and co-treating with a binding agent (BA) could enhance durability so that they only need to be treated every 2 to 3 years.The overall goal of this early-phase study is therefore to develop new, practical, scalable prototypes for EBs, which have been adapted to trap house-entering mosquitoes before they can attack the occupants, and can be readily installed in most rural African houses. We propose the following objectives for this early-phase study:1. Re-assess the insecticidal efficacy of the previously evaluated experimental prototype EBs against An. funestus and An. arabiensis in experimental huts at 12, 18, 24 and 30 months post-treatment, to demonstrate long-term efficacy when co-treated with BA.2. Develop a new EB trap design in a readily-manufactured "on a roll" format, together with broadly-scalable installation procedures, and demonstrate successful installation that reduces mosquito biting nuisance by >80% and assess user perceptions, in a random sample of rural Tanzanian houses.3. Demonstrate equivalent insecticidal efficacy of the scalable EB trap-on-a-roll format to the previous experimental prototype, using experimental huts to measure impact on mosquito survival.

屋檐挡板（EBS）是一种使用广泛可用的净材料的简单住房修饰，可以用现有的杀虫剂配方处理。经过处理的EBS和窗户屏幕进入房屋后，将蚊子捕获在房屋内，并在试图再次退出时迫使它们与杀虫剂接触。事实证明，经过杀虫剂处理的EBS的实验原型是在坦桑尼亚南部标准化的实验小屋中杀死疟疾载体的室内残留喷雾的替代品。 EBs required >5 times less insecticide than IRS, and co-treating with a binding agent (BA) could enhance durability so that they only need to be treated every 2 to 3 years.The overall goal of this early-phase study is therefore to develop new, practical, scalable prototypes for EBs, which have been adapted to trap house-entering mosquitoes before they can attack the occupants, and can be readily installed in most rural African房屋。我们提出了这项早期研究的以下目标：1。重新评估先前评估的实验原型EB的杀虫疗效。 Funestus和An。治疗后12、18、24和30个月的实验小屋中的阿拉伯语在与BA.2共同治疗时证明了长期疗效。在易于制造的“滚动”格式以及广泛的安装程序中开发新的EB陷阱设计，并在坦桑尼亚农村房屋的随机样本中展示了成功的安装，可将蚊子咬伤的麻烦降低> 80％，并评估用户的看法。3。使用实验性小屋来衡量对蚊子存活的影响，证明了可扩展的EB陷阱格式与先前实验原型的等效性杀虫疗效。

项目成果

Participatory Development of Practical, Affordable, Insecticide-Treated Mosquito Proofing for a Range of Housing Designs in Rural Southern Tanzania

为坦桑尼亚南部农村地区的一系列住房设计参与开发实用、经济实惠、经过杀虫剂处理的防蚊技术

• DOI: 10.21203/rs.3.rs-1401593/v1
• 发表时间: 2022
• 作者: Msoffe R

Participatory development of practical, affordable, insecticide-treated mosquito proofing for a range of housing designs in rural southern Tanzania.

• DOI: 10.1186/s12936-022-04333-0
• 发表时间: 2022-11-05
• 期刊: MALARIA JOURNAL
• 影响因子: 3
• 作者: Msoffe, Rogath;Hewitt, Matilda;Masalu, John P.;Finda, Marcelina;Kavishe, Deogratius R.;Okumu, Fredros O.;Mpolya, Emmanuel A.;Kaindoa, Emmanuel W.;Killeen, Gerry F.
• 通讯作者: Killeen, Gerry F.