NCI CANCER GENETICS NETWORK INFORMATICS CENTER AT UCI

描述：(申请人描述) 癌症遗传学网络将在全国范围内包括8个参与中心， 每个中心都可以访问资源、信息和专业知识 在癌症遗传学方面，来自NCI以及网络中的其他中心。 我们提出了一个先进的中央信息管理系统(CIMS) 作为信息技术基础设施的一部分，这将包括 为癌症遗传学网络参与中心提供服务的虚拟网络 研究社区。CIMS将允许参与中心收集、 以安全、可靠的 保密的时尚。我们建议的中央资讯管理系统 将利用当前的互联网基础设施与 交易安全软件的最新技术进展 能力。具体目标是：1)设计、实施和维护 将作为存储库的中央信息管理系统(CIMS) 获取同意参与癌症遗传学研究的个人的数据 网络；2)保护同意的个人的机密性 参与癌症遗传学网络；3)提供教育和 癌症遗传学网络参与中心的技术支持。它是 预计网络信息系统将管理/维护 万名S个人信息分布在千名S家庭中。 从参与未来网络的个人获得的生物样本 研究项目将被编目和跟踪。拟建的中环 信息管理系统(CIMS)考虑到了大量的 癌症遗传学网络将收集的数据，以及 网络的关键组件。癌症遗传学网络的设计 CIMS体系结构是一种非常经济实惠的解决方案 性能和可扩展性，并准备迎接下一代的挑战 千禧年。

DESCRIPTION: (Applicant's Description) The Cancer Genetics Network will include 8 participating centers nationwide, where each center would have access to resources, information, and expertise in cancer genetics from NCI, as well as the other centers in the Network. We propose a state-of-the-art Central Information Management System (CIMS) to be a part of the Information Technology infrastructure, that will include a virtual network serving Cancer Genetics Network participating centers and research communities. The CIMS will allow participating centers to collect, manage, and analyze large volumes of diverse data in a secure and confidential fashion. Our proposed Central Information Management System will take advantage of current Internet infrastructure combined with the latest technological advances of software in transaction security capability. The specific aims are to: 1) Design, implement, and maintain a Central Information Management System (CIMS) that will serve as a repository for data of individuals who consent to participate in the Cancer Genetics Network; 2) Protect the confidentiality of individuals who consent to participate in the Cancer Genetics Network; 3) Provide education and technical support for Cancer Genetics Network participating centers. It is projected that the Network information system will manage/maintain information on 10,000's of individuals distributed among 1000's of families. Biosamples obtained from individuals participating in future Network research projects will be cataloged and tracked. The proposed Central Information Management System (CIMS) takes into account the large volume of data that will be collected by the Cancer Genetics Network, as well as the key components of the Network. The design of the Cancer Genetics Network CIMS architecture is a very cost-effective solution without compromising performance and scalability and prepares for the challenges of the next millennium.