GENETIC EPIDEMIOLOGY OF PANCREAS CANCER FAMILIES: A CANCER GENETICS NETWORK PILO

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项癌症遗传学网络(CGN)试点提案的目标是确定胰腺癌的遗传、环境和家族史风险因素。由于胰腺癌患者的快速死亡率较高(不到三年)，由八个中心组成的癌症遗传学网络中现有的胰腺癌家族数据库相对较小。UCI将与西雅图的西北癌症遗传网络(到目前为止已经收集了大约150例胰腺病例和250名亲属)合作，扩大这个数据库，为CGN进行更广泛的数据分析研究做准备。将共享的数据库是UCI IRB批准的HS#97-464，这是所有八个癌症遗传中心安全使用的信息学数据库。西北癌症遗传中心没有直接参与UCI受试者或UCI受试者可识别的数据。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of this Cancer Genetics Network (CGN) pilot proposal is to identify genetic, environmental and family history risk factors for pancreas cancer. Because of the high rapid mortality rate for pancreatic cancer patients (less than three years), the existing pancreas cancer family database in the Cancer Genetics Network of eight centers is relatively small. UCI will collaborate with the Northwest Cancer Genetic Network in Seattle (who has collected about 150 pancreatic cases and 250 relatives to date) to expand this database in order to prepare for more extensive data analysis research by the CGN. The database that will be shared is UCI IRB approved HS# 97-464 the Informatics Database used securely by all eight Cancer Genetic Centers. There is no direct involvement of the Northwest Cancer Genetic Center with UCI subjects or with UCI subject identifiable data.