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Non-invasive electrical stimulation of cervical spinal cord to facilitate arm & hand functional recovery in incomplete traumatic cervical spinal cord

Non-invasive electrical stimulation of cervical spinal cord to facilitate arm & hand functional recovery in incomplete traumatic cervical spinal cord
无创电刺激颈脊髓以利手臂
批准号:
MR/R001189/1
负责人:
Andrew Jackson
金额:
$30.08万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2017
资助国家:
英国
项目状态:
已结题
起止时间:
2017 至 --

项目摘要

项目成果

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中文摘要
翻译
脊髓损伤可导致手臂和手部瘫痪,对生活质量造成毁灭性后果。该合作项目旨在开发一种新的方法,通过皮肤对脊髓进行无痛电刺激来恢复上肢功能。新的刺激模式将在动物实验中开发和优化,然后与患有脊髓损伤的人类志愿者进行测试。我们希望了解经皮脊髓刺激可以提高神经系统的兴奋性和增强神经可塑性的机制,从而对上肢瘫痪患者的日常任务产生持久的有益影响。
英文摘要
Injuries to the spinal cord can lead to paralysis of the arms and hands with devastating consequences for quality of life. This collaborative project aims to develop a new approach to restoring function to the upper-limb using painless electrical stimulation of the spinal cord delivered through the skin. The novel stimulation patterns will be developed and optimised in animal experiments before testing with human volunteers suffering from spinal cord injury. We hope to understand the mechanisms by which transcutaneous spinal stimulation can boost the excitability of the nervous system and enhance neuroplasticity, leading to lasting beneficial effects on everyday tasks for those suffering with upper-limb paralysis.
期刊论文(3)
专著(0)
科研奖励(0)
会议论文
A high-performance 8 nV/vHz 8-channel wearable and wireless system for real-time monitoring of bioelectrical signals.
高性能 8 nV/vHz 8 通道可穿戴无线系统,用于实时监测生物电信号。
DOI: 10.1186/s12984-019-0629-2
发表时间: 2019
期刊: Journal of neuroengineering and rehabilitation
影响因子: 5.1
作者: [Petkos K]
通讯作者: Petkos K
DOI: 10.1088/1741-2552/abe358
发表时间: 2021-03-22
期刊: Journal of neural engineering
影响因子: 4
作者: [Guiho T, Baker SN, Jackson A]
通讯作者: Jackson A
Mechanisms for Microcephaly, Cancer and Autoinflammation
  • 批准号:
    MC_UU_00035/10
  • 项目类别:
    Intramural
  • 资助金额:
    $551.22万
  • 财政年份:
    2023
  • 负责人:
    Andrew Jackson
  • 依托单位:
Closed-loop Neural Interface Technologies (Close-NIT) Network Plus
  • 批准号:
    EP/W035081/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $140.95万
  • 财政年份:
    2022
  • 负责人:
    Andrew Jackson
  • 依托单位:
Discovery Projects - Grant ID: DP210101354
  • 批准号:
    ARC : DP210101354
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $22.39万
  • 财政年份:
    2021
  • 负责人:
    Andrew Jackson
  • 依托单位:
From Microcephaly to Genome Stability,Inflammation and Growth Regulation
  • 批准号:
    MC_UU_00007/5
  • 项目类别:
    Intramural
  • 资助金额:
    $576.45万
  • 财政年份:
    2018
  • 负责人:
    Andrew Jackson
  • 依托单位:
国内基金
海外基金
基于深穿透拉曼光谱的安全光照剂量的深层病灶无创检测与深度预测
  • 批准号:
    82372016
  • 项目类别:
    面上项目
  • 资助金额:
    48.00万元
  • 批准年份:
    2023
  • 负责人:
    林俐
  • 依托单位: