Non-invasive electrical stimulation of cervical spinal cord to facilitate arm & hand functional recovery in incomplete traumatic cervical spinal cord
Non-invasive electrical stimulation of cervical spinal cord to facilitate arm & hand functional recovery in incomplete traumatic cervical spinal cord
批准号:
MR/R001189/1
负责人:
Andrew Jackson
金额:
$30.08万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2017
资助国家:
英国
项目状态:
已结题
起止时间:
2017 至 --
中文摘要
脊髓损伤可导致手臂和手部瘫痪,对生活质量造成毁灭性后果。该合作项目旨在开发一种新的方法,通过皮肤对脊髓进行无痛电刺激来恢复上肢功能。新的刺激模式将在动物实验中开发和优化,然后与患有脊髓损伤的人类志愿者进行测试。我们希望了解经皮脊髓刺激可以提高神经系统的兴奋性和增强神经可塑性的机制,从而对上肢瘫痪患者的日常任务产生持久的有益影响。
英文摘要
Injuries to the spinal cord can lead to paralysis of the arms and hands with devastating consequences for quality of life. This collaborative project aims to develop a new approach to restoring function to the upper-limb using painless electrical stimulation of the spinal cord delivered through the skin. The novel stimulation patterns will be developed and optimised in animal experiments before testing with human volunteers suffering from spinal cord injury. We hope to understand the mechanisms by which transcutaneous spinal stimulation can boost the excitability of the nervous system and enhance neuroplasticity, leading to lasting beneficial effects on everyday tasks for those suffering with upper-limb paralysis.
期刊论文(3)
专著(0)
科研奖励(0)
会议论文
A high-performance 8 nV/vHz 8-channel wearable and wireless system for real-time monitoring of bioelectrical signals.
高性能 8 nV/vHz 8 通道可穿戴无线系统,用于实时监测生物电信号。
DOI:
10.1186/s12984-019-0629-2
发表时间:
2019
期刊:
Journal of neuroengineering and rehabilitation
影响因子:
5.1
作者:
[Petkos K]
通讯作者:
Petkos K
DOI:
10.1088/1741-2552/abe358
发表时间:
2021-03-22
期刊:
Journal of neural engineering
影响因子:
4
作者:
[Guiho T, Baker SN, Jackson A]
通讯作者:
Jackson A
Mechanisms for Microcephaly, Cancer and Autoinflammation
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批准号:MC_UU_00035/10
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项目类别:Intramural
-
资助金额:$551.22万
-
财政年份:2023
-
负责人:Andrew Jackson
-
依托单位:
Closed-loop Neural Interface Technologies (Close-NIT) Network Plus
-
批准号:EP/W035081/1
-
项目类别:Research Grant
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资助金额:$140.95万
-
财政年份:2022
-
负责人:Andrew Jackson
-
依托单位:
Discovery Projects - Grant ID: DP210101354
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批准号:ARC : DP210101354
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项目类别:Discovery Projects
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资助金额:$22.39万
-
财政年份:2021
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负责人:Andrew Jackson
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依托单位:
From Microcephaly to Genome Stability,Inflammation and Growth Regulation
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批准号:MC_UU_00007/5
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项目类别:Intramural
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资助金额:$576.45万
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财政年份:2018
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负责人:Andrew Jackson
-
依托单位:
A Collaborative Initiative to Develop Animal Trypanosomiasis Vaccines in Brazil
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批准号:BB/R021139/1
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项目类别:Research Grant
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资助金额:$3.71万
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财政年份:2018
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负责人:Andrew Jackson
-
依托单位:
New approaches to a livestock trypanosomiasis vaccine: targeting the bite-site by immunization with novel metacyclic-stage parasite antigens
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批准号:BB/S001980/1
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项目类别:Research Grant
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资助金额:$83.05万
-
财政年份:2018
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负责人:Andrew Jackson
-
依托单位:
Variant antigen profiling: a novel genomic tool for diagnosis and surveillance of animal African trypanosomiasis.
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批准号:BB/M022811/1
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项目类别:Research Grant
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资助金额:$59.28万
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财政年份:2016
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负责人:Andrew Jackson
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依托单位:
Human Genetics Unit Senior Clinical Fellowship
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批准号:MR/K501062/1
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项目类别:Fellowship
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资助金额:$50.1万
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财政年份:2012
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负责人:Andrew Jackson
-
依托单位:
Pilot study: A fully-automated system for positive reinforcement training of group-housed non-human primates
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批准号:G1100113/1
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项目类别:Research Grant
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资助金额:$9.37万
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财政年份:2012
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负责人:Andrew Jackson
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依托单位:
UK-Japan Neural Interfaces N+N Workshop
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批准号:EP/H043632/1
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项目类别:Research Grant
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资助金额:$1.01万
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财政年份:2010
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负责人:Andrew Jackson
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依托单位:
Ultra Low Power Implantable Platform for Next Generation Neural Interfaces
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批准号:EP/H051570/1
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项目类别:Research Grant
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资助金额:$32.83万
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财政年份:2010
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负责人:Andrew Jackson
-
依托单位:
Optimal feedback control of a neuromotor interface
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批准号:G0802195/1
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项目类别:Research Grant
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资助金额:$58.26万
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财政年份:2009
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负责人:Andrew Jackson
-
依托单位:
Functional studies of mutant nucleases in a genetic model of inflammatory and viral disease.
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批准号:MC_EX_G0601852
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项目类别:Fellowship
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资助金额:$194.77万
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财政年份:2007
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负责人:Andrew Jackson
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依托单位:
Virus and Host Interactions of the Nucleocapsid Proteins Encoded by a Plant Nucleorhabdovirus
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批准号:0316907
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项目类别:Continuing Grant
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资助金额:$31.48万
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财政年份:2003
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负责人:Andrew Jackson
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依托单位:
Analysis of Nucleorhabdovirus Replication in Plant and Yeast Cells
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批准号:9904810
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项目类别:Continuing Grant
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资助金额:$21.0万
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财政年份:1999
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负责人:Andrew Jackson
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依托单位:
Protein Interactions During Replication of a Plant Rhabodovirus
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批准号:9418086
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项目类别:Continuing Grant
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资助金额:$42.4万
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财政年份:1995
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负责人:Andrew Jackson
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依托单位:
Replication Strategy and Control of a Plant Rhabdovirus
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批准号:9017623
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项目类别:Continuing Grant
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资助金额:$27.0万
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财政年份:1991
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负责人:Andrew Jackson
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依托单位:
Genome Structure and Replication of a Plant Rhabdovirus
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批准号:8716467
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项目类别:Continuing Grant
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资助金额:$23.84万
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财政年份:1988
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负责人:Andrew Jackson
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依托单位:
Organization and Structure of the Genomic and Messenger RNA's of a Plant Rhabdovirus
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批准号:8545575
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项目类别:Continuing Grant
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资助金额:$10.25万
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财政年份:1986
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负责人:Andrew Jackson
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依托单位:
Organization and Structure of the Genomic and Messenger RNA's of a Plant Rhabdovirus
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批准号:8318007
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项目类别:Continuing Grant
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资助金额:$18.8万
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财政年份:1984
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负责人:Andrew Jackson
-
依托单位:
国内基金
海外基金
基于深穿透拉曼光谱的安全光照剂量的深层病灶无创检测与深度预测
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批准号:82372016
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项目类别:面上项目
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资助金额:48.00万元
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批准年份:2023
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负责人:林俐
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依托单位: