CHEMICAL CONCEPTS FOR IMPROVED GLASS IONOMER SYSTEMS

改进玻璃离聚物系统的化学概念

• 批准号: 2897088
• 负责人: Bill M. Culbertson
• 金额: $ 20.83万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-30 至 2001-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2897088
• 关键词: biomaterial development /preparation; biomaterial evaluation; carboxylate; chemical property; copolymer; dental adhesive /sealant; dental material wear; dental materials; gas chromatography; human tissue; nuclear magnetic resonance spectroscopy; oral facial restoration material; physical property; polyacrylate; polymerization; polymers; tensile strength; visible light

DESCRIPTION (Adapted from the Applicant's Abstract): Currently available glass ionomer formulations have many advantages, including adhesion to tooth structure and fluoride release, that contribute to their increasingly popular use in restorative dentistry and other applications. However, these materials suffer from relatively low compressive, tensile and flexural strengths compared to other longer-lasting restorative materials. The overall goal of this research is to develop polymeric matrix formulations for visible light-cured glass ionomer materials with improved properties. The three Aims are: 1.) to develop optimum backbone formulations with superior properties; 2.) to make these improved formulations curable by visible light and to optimize these formulations; and 3.) to further develop these formulations for additional improvements. The chemical approach that will dominate these physical improvements will focus on improving the copolymer flexibility and the availability of carboxylic acid groups for salt-bridge formation, an approach for which significant strength improvements have been demonstrated. The experimental approach will be to first optimize those compositions known to have maximum flexural strength, then to compare other properties such as working and setting times, tensile and compressive strengths, thermal expansion coefficient, solubility, adhesion to tooth structure, and fluoride release. A commercially available material will be used as control.

描述(改编自申请人摘要)：目前可用 玻璃离子制剂有许多优点，包括对牙齿的粘附性 结构和氟化物的释放，这有助于它们越来越多地 在修复牙科和其他应用中广泛使用。然而，这些 材料具有相对较低的压缩、拉伸和弯曲性能。 与其他更持久的修复材料相比，它具有更强的性能。这个 这项研究的总体目标是开发聚合物基质配方 用于性能得到改善的可见光固化玻璃离子材料。 这三个目标是：1.)要开发最佳骨架配方，请使用 优越的性能；2.)为了使这些改进的配方可以通过以下方式固化 可见光并优化这些配方；3.)进一步发展 这些配方需要进一步的改进。化学方法，即 将主导这些物理改进将专注于改善 共聚物的柔韧性和羧酸基的可用性 盐桥形成，这是一种具有显著强度的方法 已经证明了改进的效果。实验方法将是 首先优化那些已知具有最大弯曲强度的组合物， 然后比较其他性能，如工作和凝结时间、抗拉强度 以及抗压强度、热膨胀系数、溶解度、 与牙齿结构粘合，并释放氟化物。一种商业上可用的 材料将用作对照。