Development of blood-based biomarkers for the early detection of brain amyloid and the investigation of the natural history of Alzheimer’s Disease.

开发基于血液的生物标志物，用于早期检测脑淀粉样蛋白和研究阿尔茨海默病的自然史。

• 批准号: nhmrc : 1138673
• 负责人: Dr Blaine Roberts
• 金额: $ 48.63万
• 依托单位国家: 澳大利亚
• 项目类别: Targeted Calls
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/development-blood-based-alzheimers-disease/1318822
• 关键词: Development; blood; based; biomarkers; early

To have a direct impact on the diagnosis and treatment of Alzheimer’s and other neurodegenerative diseases we need a detailed molecular understanding of the proteins that drive the disease. My laboratory develops and applies the most advanced analytical tools available to develop blood-based markers that can detect the development of Alzheimer’s disease before symptoms occur. This Fellowship will allow me to expand our understanding of the natural history of Alzheimer’s disease.

为了对阿尔茨海默氏症和其他神经退行性疾病的诊断和治疗产生直接影响，我们需要对驱动疾病的蛋白质进行详细的分子理解。我的实验室开发并应用了现有的最先进的分析工具来开发基于血液的标记物，可以在症状出现之前检测阿尔茨海默病的发展。这一奖学金将使我能够扩大我们对阿尔茨海默病自然病史的理解。