DETECTION AND RISK OF EHRLICHIAL DISEASES

描述（改编自申请人摘要）：人粒细胞 埃里希体病（HGE）和人单核细胞埃里希体病（HME）正在出现 这两种疾病的年发病率是 报告的人类埃立克体病病例超过600例， 过去十年。 本研究的目的是检测是否存在 纽约HGE制剂和相关埃立克体病原体的分布 状态 具体而言，申请人将评估犬的效用 血清学评估流行区HGE风险，2）测量犬 在很少或没有报告HGE病例的地区，3）检测 肩胛硬蜱和美洲钝眼蜱中埃立克体的存在 种及相关病原体，以及4）建立犬血清库和 蜱虫储存库，用于未来对新出现的蜱虫传播的 该地区的疾病。

DESCRIPTION (adapted from applicant's abstract): Human granulocytic ehrlichiosis (HGE) and human monocytic ehrlichiosis (HME) are emerging tick-borne disease in the U.S. Annual incidence of both disease is increasing, with more than 600 cases of human ehrlichiosis reported in the last ten years. The purpose of this study is to detect the presence and distribution of the HGE agent and related ehrlichial pathogens in New York State. Specifically, the applicant will evaluate the utility of canine serology to assess risk for HGE in an endemic area, 2) measure canine seroprevalence in areas where few or no cases of HGE are reported, 3) test Ixodes scapularis and Amblyomma americanum for the presence of Ehrlichia species and related pathogens, and 4) establish a canine serum bank and a tick depository for future retrospective studies on emerging tick-borne diseases in the region.