SYMPTOM MONITORING IN CHILDHOOD ASTHMA--A CLINICAL TRIAL

描述：(改编自研究人员摘要)哮喘是最常见的 儿童常见病、慢性病及其患病率 在美国，发病率和死亡率正在上升。不准确 对症状严重程度的感知被认为是延误的主要原因 在治疗哮喘方面，这会导致发病率和死亡率。这个 儿童哮喘症状监测研究：一项临床试验 旨在：a)评估三种不同强度的 哮喘患儿及其家属的症状监测 生理、功能、心理和卫生保健利用 结果，以及b)描述受试者的症状监测经验 以及它们随后对监测战略的遵守。二 将使用互补的方法学方法来实现以下目标 建议的研究。该研究包括一项随机临床试验，以 评价不同强度肺监测的效果 对哮喘儿童的监测和描述性研究 家庭的经历。具体地说，研究目的是比较 三组哮喘儿童(每天服用两次的儿童 使用家庭峰值流量计进行客观的肺部监测， 只在有症状的时候接受监测，无论是哪个目标都有一个高峰 流量计或主观症状评估)与临床相关 结果、卫生保健利用和生活质量；以及2)描述 患者/家属的背景特征、症状 监测经验，以及随后对监测的坚持 战略，包括遵守和不遵守的理由 监控策略。临床试验数据的分析将是 重复测量分析比较干预前后的生理， 功能、生活质量和卫生保健利用结果。 描述性数据将包括父母和孩子对 监测经验、知识和后续行为 关于遵守拟议的监测战略。

DESCRIPTION: (Adapted from investigator's abstract) Asthma is the most common chronic illness in childhood and its prevalence as well as its morbidity and mortality are increasing in the United States. Inaccurate perception of symptom severity is believed to be a major reason for delays in the treatment of asthma, contributing to morbidity and mortality. The study, Symptom Monitoring in Childhood Asthma: A Clinical Trial, is designed to: a) assess the effects of three different intensities of symptom monitoring by children with asthma and their families on physiological, functional, psychosocial, and health care utilization outcomes, and b) to describe the symptom monitoring experiences of subjects and their subsequent adherence to the monitoring strategy. Two complementary methodological approaches will be used to achieve the aims of the proposed research. The study consists of a randomized clinical trial to evaluate the effects of the different intensities of pulmonary monitoring for children with asthma, and a descriptive study of the monitoring experiences of the family. Specifically, the research aims are to compare three groups of children with asthma (those who receive twice daily objective pulmonary monitoring with a home peak flow meter, those who receive monitoring only at symptomatic times, either objective with a peak flow meter or subjective symptom evaluation) with regard to clinical outcomes, health care utilization and quality of life; and 2) to describe the background characteristics of patients/families, their symptom monitoring experiences, and subsequent adherence to the monitoring strategies, including the reasons given for adherence and non-adherence with the monitoring strategy. Analysis of the clinical trial data will be a repeated measure analysis comparing pre and post-intervention physiological, functional, quality of life, and health care utilization outcomes. Descriptive data will include both parents' and children's perceptions of the monitoring experience and their knowledge and subsequent behaviors around adherence with the proposed monitoring strategy.