SYMPTOM MONITORING IN CHILDHOOD ASTHMA--A CLINICAL TRIAL

儿童哮喘的症状监测——临床试验

• 批准号: 2873112
• 负责人: HANNELORE YOOS
• 金额: $ 20.36万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-02-01 至 2001-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2873112
• 关键词: African American; adolescence (12-20); asthma; caucasian American; clinical research; clinical trials; experience; health care service utilization; human subject; middle childhood (6-11); nursing care evaluation; outcomes research; patient care management; patient monitoring device; pediatric nursing; quality of life; respiratory airflow measurement; respiratory disorder epidemiology; respiratory function; sign /symptom

DESCRIPTION: (Adapted from investigator's abstract) Asthma is the most common chronic illness in childhood and its prevalence as well as its morbidity and mortality are increasing in the United States. Inaccurate perception of symptom severity is believed to be a major reason for delays in the treatment of asthma, contributing to morbidity and mortality. The study, Symptom Monitoring in Childhood Asthma: A Clinical Trial, is designed to: a) assess the effects of three different intensities of symptom monitoring by children with asthma and their families on physiological, functional, psychosocial, and health care utilization outcomes, and b) to describe the symptom monitoring experiences of subjects and their subsequent adherence to the monitoring strategy. Two complementary methodological approaches will be used to achieve the aims of the proposed research. The study consists of a randomized clinical trial to evaluate the effects of the different intensities of pulmonary monitoring for children with asthma, and a descriptive study of the monitoring experiences of the family. Specifically, the research aims are to compare three groups of children with asthma (those who receive twice daily objective pulmonary monitoring with a home peak flow meter, those who receive monitoring only at symptomatic times, either objective with a peak flow meter or subjective symptom evaluation) with regard to clinical outcomes, health care utilization and quality of life; and 2) to describe the background characteristics of patients/families, their symptom monitoring experiences, and subsequent adherence to the monitoring strategies, including the reasons given for adherence and non-adherence with the monitoring strategy. Analysis of the clinical trial data will be a repeated measure analysis comparing pre and post-intervention physiological, functional, quality of life, and health care utilization outcomes. Descriptive data will include both parents' and children's perceptions of the monitoring experience and their knowledge and subsequent behaviors around adherence with the proposed monitoring strategy.

描述：（改编自研究者的摘要）哮喘是最常见的 儿童期常见的慢性病及其患病率和发病率 美国的发病率和死亡率正在增加。 不准确 对症状严重程度的感知被认为是延误的主要原因 在哮喘治疗中，导致发病率和死亡率。 这 研究“儿童哮喘症状监测：临床试验”是 旨在： a) 评估三种不同强度的影响 哮喘儿童及其家人的症状监测 生理、功能、心理和保健利用 结果，以及 b) 描述受试者的症状监测经历 以及他们随后对监测策略的遵守情况。 二 将采用补充方法方法来实现以下目标： 拟议的研究。 该研究包括一项随机临床试验 评估不同强度肺监测的效果 对于患有哮喘的儿童，以及监测的描述性研究 家庭的经历。 具体来说，研究目的是比较 三组患有哮喘的儿童（每天接受两次治疗的儿童） 使用家用峰值流量计进行客观的肺部监测， 仅在出现症状时接受监测，无论目标是否达到峰值 流量计或主观症状评估）关于临床 结果、医疗保健利用和生活质量； 2）描述 患者/家庭的背景特征、症状 监测经验以及后续监测的遵守情况 策略，包括遵守和不遵守策略的原因 监测策略。 对临床试验数据的分析将是 比较干预前后生理的重复测量分析， 功能、生活质量和医疗保健利用结果。 描述性数据将包括父母和孩子的看法 监控经验及其知识和后续行为 围绕遵守拟议的监测战略。

项目成果

Peak flow meters in childhood asthma: parent report of use and perceived usefulness.

儿童哮喘中的峰值流量计：家长的使用报告和感知有用性。

• 发表时间: 2002
• 期刊: Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners.
• 作者: McMullen,AnnH;Yoos,HLorrie;Kitzman,Harriet
• 通讯作者: Kitzman,Harriet

Symptom monitoring in childhood asthma: a randomized clinical trial comparing peak expiratory flow rate with symptom monitoring.

儿童哮喘的症状监测：一项比较呼气峰流速与症状监测的随机临床试验。

• DOI: 10.1016/s1081-1206(10)62010-8
• 发表时间: 2002
• 期刊: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
• 作者: Yoos,HLorrie;Kitzman,Harriet;McMullen,Ann;Henderson,Charles;Sidora,Kimberly
• 通讯作者: Sidora,Kimberly