SYMPTOM MONITORING IN CHILDHOOD ASTHMA--A CLINICAL TRIAL

儿童哮喘的症状监测——临床试验

• 批准号: 2655415
• 负责人: HANNELORE YOOS
• 金额: $ 23.66万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-02-01 至 2000-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2655415
• 关键词: African American; adolescence (12-20); asthma; caucasian American; clinical research; clinical trials; experience; health care service utilization; human subject; middle childhood (6-11); nursing care evaluation; outcomes research; patient care management; patient monitoring device; pediatric nursing; quality of life; respiratory airflow measurement; respiratory disorder epidemiology; respiratory function; sign /symptom

DESCRIPTION: (Adapted from investigator's abstract) Asthma is the most common chronic illness in childhood and its prevalence as well as its morbidity and mortality are increasing in the United States. Inaccurate perception of symptom severity is believed to be a major reason for delays in the treatment of asthma, contributing to morbidity and mortality. The study, Symptom Monitoring in Childhood Asthma: A Clinical Trial, is designed to: a) assess the effects of three different intensities of symptom monitoring by children with asthma and their families on physiological, functional, psychosocial, and health care utilization outcomes, and b) to describe the symptom monitoring experiences of subjects and their subsequent adherence to the monitoring strategy. Two complementary methodological approaches will be used to achieve the aims of the proposed research. The study consists of a randomized clinical trial to evaluate the effects of the different intensities of pulmonary monitoring for children with asthma, and a descriptive study of the monitoring experiences of the family. Specifically, the research aims are to compare three groups of children with asthma (those who receive twice daily objective pulmonary monitoring with a home peak flow meter, those who receive monitoring only at symptomatic times, either objective with a peak flow meter or subjective symptom evaluation) with regard to clinical outcomes, health care utilization and quality of life; and 2) to describe the background characteristics of patients/families, their symptom monitoring experiences, and subsequent adherence to the monitoring strategies, including the reasons given for adherence and non-adherence with the monitoring strategy. Analysis of the clinical trial data will be a repeated measure analysis comparing pre and post-intervention physiological, functional, quality of life, and health care utilization outcomes. Descriptive data will include both parents' and children's perceptions of the monitoring experience and their knowledge and subsequent behaviors around adherence with the proposed monitoring strategy.

描述：（改编自研究者摘要）哮喘是 儿童常见慢性病及其患病率和 在美国，发病率和死亡率正在上升。 不准确 对症状严重程度的感知被认为是延误的主要原因 在哮喘治疗中，导致发病率和死亡率。 的 一项名为《儿童哮喘症状监测：临床试验》的研究， 目的是：a）评估三种不同强度的 哮喘儿童及其家属对哮喘症状的监测 生理、功能、社会心理和卫生保健利用 结果，和B）描述受试者的症状监测经验 以及他们随后对监测战略的遵守情况。 两 将采用补充性的方法来实现以下目标： 拟议的研究。 该研究包括一项随机临床试验， 评价不同强度肺监护的效果 对哮喘儿童进行了一项描述性研究， 家庭的经历。 具体而言，研究目的是比较 三组哮喘儿童（每天接受两次 使用家用峰值流量计进行客观肺监测， 仅在出现症状时接受监测， 流量计或主观症状评估） 结果，医疗保健利用和生活质量; 2）描述 患者/家属的背景特征、症状 监测经验，以及随后对监测的遵守情况 战略，包括遵守和不遵守的理由 监测战略。 临床试验数据分析将是 重复测量分析比较干预前和干预后的生理， 功能、生活质量和医疗保健利用结果。 描述性数据将包括父母和儿童对 监测经验、知识和后续行为 围绕遵守拟议的监测战略。