DIAGNOSIS AND COUNSELING FOR HEMOGLOBIN ABNORMALITIES

血红蛋白异常的诊断和咨询

• 批准号: 6241946
• 负责人: SAMIR BALLAS
• 金额: $ 12.53万
• 依托单位: CHILDREN'S HOSP OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-01 至 1998-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6241946
• 关键词: African American; Asian Americans; Hispanic Americans; behavioral /social science research tag; blood disorder diagnosis; disease /disorder proneness /risk; disease carrier state; early diagnosis; genetic counseling; health education; hemoglobin Ss; hemoglobinopathy; human pregnant subject; human subject; newborn human (0-6 weeks); prenatal diagnosis; sickle cell anemia; spouses

This project is a modified continuation of the newborn screening study which was previously funded. Specific approaches of the current project include: 1. Identification, testing, counseling, and education of pregnant women who are at risk to be carriers of Hb S gene or other abnormal hemoglobins. Pregnant women at risk (Black, Hispanics, Asians,....) will be identified in our prenatal clinic and tested for the presence of hemoglobinopathies. Those that are carriers of Hb S gene or other abnormal hemoglobins will be followed in our Center for counseling and education. The spouses of these patients will also be tested and further counseling and education will ensue including the initiation of the process of prenatal diagnosis. 2. Counseling, education, and possible prenatal diagnosis of patients with sickle cell anemia who became pregnant. The spouses of these patients will also be tested as was mentioned above. 3. Confirmatory testing of newborns at our institution who are found to be at risk to have hemoglobinopathies by the State Newborn Screening Project.

本项目是新生儿筛查研究的改良延续