CORE--PATIENTS AND STATISTICAL ANALYSIS

人类受试者和统计学的总体目标 分析核心单元（核心C）将提供支持服务， 将提高质量、生产率和成本效益 人类受试者的研究，包括提供所需的 队列维护服务、数据输入和管理服务， 和先进的统计专业知识。主 本研究的核心功能分为五大类 类别： (l)设计和完善人类受试者研究， 评估协议，包括纵向的最新进展， 研究技术和建立在集体和多样化的基础上， 中心调查人员的专业知识; (2)受试者招募和保留（队列维持）支持 为中心研究者提供服务; (3)数据管理服务，从数据协助 输入和编辑，文件设置，文件维护和合并， 数据库的总存档; (4)多变量和纵向统计分析 数据库，特别是复杂数据的应用 分析策略和促进交叉研究和Meta， 分析;以及 (5)高级统计技术、新的 软件统计和图形包，并有前途 事后和交叉研究数据分析的机会 与中心主题相关的问题。

The overall objective of the Human Subjects and Statistical Analysis Core Unit (Core C) is to provide support services that will improve the quality, the productivity, and cost effectiveness of the human subjects research, including the provision of needed cohort maintenance services, data entry and management services, and advanced statistical expertise to investigators. The primary functions of this research core are divided into five major categories: (l) design and refinement of human subjects research studies and assessment protocols, incorporating recent advances in longitudinal research techniques and building upon the collective and diverse expertise of the Center's investigators; (2) subject recruitment and retention (cohort maintenance) support services for Center investigators; (3) data management services, ranging from assistance with data entry and editing, file set-up, file maintenance and mergers to master archiving of databases; (4) statistical analyses of multivariate and longitudinal databases, especially the application of sophisticated data analytic strategies and facilitation of cross-study and meta- analytic analyses; and (5) seminars and training in advanced statistical techniques, new software statistical and graphics packages, and promising opportunities for post hoc and cross-study data analyses on questions relevant to the Center's theme.